Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12356342 | 1.00 | CYP1A2 (0.60) | CYP1A2TSHRSLC1A1GABRR1LTA4H | |
| SCHEMBL1835138 | 1.00 | CYP1A2 (0.60) | CYP1A2TSHRSLC1A1GABRR1LTA4H | |
| SCHEMBL233224 | 0.85 | LTA4H (0.56) | CYP1A2TSHRSLC1A1GABRR1LTA4H | |
| SCHEMBL3595528 | 0.84 | CYP1A2 (0.62) | CYP1A2SLC1A1GABRR1LTA4HBLM | |
| Hydrochloric Acid SCHEMBL1228512 | 0.84 | LTA4H (0.55) | CYP1A2TSHRSLC1A1GABRR1LTA4H | |
| SCHEMBL14360056 | 0.84 | LTA4H (0.55) | CYP1A2TSHRSLC1A1GABRR1LTA4H | |
| SCHEMBL12951358 | 0.82 | TSHR (0.52) | CYP1A2TSHRSLC1A1MEN1KMT2A | |
| SCHEMBL265551 | 0.82 | TSHR (0.52) | CYP1A2TSHRSLC1A1MEN1KMT2A | |
| SCHEMBL11062326 | 0.82 | TSHR (0.52) | CYP1A2TSHRSLC1A1MEN1KMT2A | |
| SCHEMBL16300949 | 0.82 | TSHR (0.52) | CYP1A2TSHRSLC1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490271-B | Methods and materials for making simvastatin and related compounds | UNIV CALIFORNIA | 2014-03-12 | — | — | CN | claimed |
| EP-3356375-A1 | PROCESS FOR RECOVERING A MIXTURE COMPRISING A (THIO)PHOSPHORIC ACID DERIVATIVE | BASF SE (DE) | 2018-08-08 | — | — | EP | disclosed |
| US-9760030-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2017-09-12 | — | — | US | disclosed |
| US-9392785-B2 | Use of esteramides as solvents, novel esteramides and process for preparing esteramides | RHODIA OPERATIONS (FR) | 2016-07-19 | — | — | US | disclosed |
| US-9392785-B2 | Use of esteramides as solvents, novel esteramides and process for preparing esteramides | RHODIA OPERATIONS (FR) | 2016-07-19 | — | — | US | disclosed |
| US-20160116853-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2016-04-28 | — | — | US | disclosed |
| US-20160054666-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KK (JP) | 2016-02-25 | — | — | US | disclosed |
| US-20150277247-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KK (JP) | 2015-10-01 | — | — | US | disclosed |
| US-20150277246-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KK (JP) | 2015-10-01 | — | — | US | disclosed |
| US-9141008-B2 | Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and imide compound | CANON KABUSHIKI KAISHA (JP) | 2015-09-22 | — | — | US | disclosed |
| US-4192882-A | SUBSTITUTED INDOLES FOR RELIEVING ANGIOTENSIN RELATED HYPERTENSION | E. R. SQUIBB & SONS, INC. (US) | 1980-03-11 | — | — | US | disclosed |
| US-4192881-A | RELIEVING ANGIOTENSIN RELATED HYPERTENSION | E. R. SQUIBB & SONS, INC. (US) | 1980-03-11 | — | — | US | disclosed |
| US-4154937-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4153725-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-05-08 | — | — | US | disclosed |
| US-4146641-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-03-27 | — | — | US | disclosed |
| US-4146639-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1979-03-27 | — | — | US | disclosed |
| US-4128653-A | Reduction of blood pressure with carboxyalkylacyl-pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1978-12-05 | — | — | US | disclosed |
| US-4105789-A | Carboxyalkylacylamino acids | E. R. SQUIBB & SONS, INC. (US) | 1978-08-08 | — | — | US | disclosed |
| US-4086338-A | HYPOTENSIVE AGENTS, ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4052511-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1977-10-04 | — | — | US | disclosed |