Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12951358 | 1.00 | TSHR (0.52) | TSHRSLC1A1MGAMGAASI | |
| SCHEMBL20767532 | 0.85 | TSHR (0.54) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL30593797 | 0.85 | TSHR (0.54) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL16489316 | 0.84 | TSHR (0.52) | TSHRKMT2ALMNAALDH1A1MAPT | |
| SCHEMBL305284 | 0.84 | TSHR (0.52) | TSHRKMT2ALMNAALDH1A1MAPT | |
| SCHEMBL7943410 | 0.84 | TSHR (0.52) | TSHRKMT2ALMNAALDH1A1MAPT | |
| SCHEMBL1835136 | 0.82 | CYP1A2 (0.60) | TSHRSLC1A1KMT2AMEN1CA12 | |
| SCHEMBL265551 | 0.82 | TSHR (0.52) | TSHRSLC1A1MGAMGAASI | |
| SCHEMBL16300949 | 0.82 | TSHR (0.52) | TSHRSLC1A1MGAMGAASI | |
| SCHEMBL1835138 | 0.82 | CYP1A2 (0.60) | TSHRSLC1A1KMT2AMEN1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107854720-A | Medicine-carried polyhydroxylated polymer embolism microball with radiography function and preparation method thereof | 苏州恒瑞迦俐生生物医药科技有限公司 | 2018-03-30 | — | — | CN | claimed |
| CN-107899066-A | Cation polyhydroxylated polymer embolism microball and preparation method thereof | 苏州恒瑞迦俐生生物医药科技有限公司 | 2018-04-13 | — | — | CN | disclosed |
| CN-107854720-A | Medicine-carried polyhydroxylated polymer embolism microball with radiography function and preparation method thereof | 苏州恒瑞迦俐生生物医药科技有限公司 | 2018-03-30 | — | — | CN | disclosed |
| US-9925528-B2 | Catalyst-controlled aliphatic C—H oxidations | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-03-27 | — | — | US | disclosed |
| EP-2513091-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-04-12 | — | — | EP | disclosed |
| US-9545449-B2 | Site-specific labeling and targeted delivery of proteins for the treatment of cancer | Advanced Proteone Therapeutics Inc. (US) | 2017-01-17 | — | — | US | disclosed |
| US-20160214097-A1 | CATALYST-CONTROLLED ALIPHATIC C-H OXIDATIONS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-07-28 | — | — | US | disclosed |
| US-20150202314-A1 | SITE-SPECIFIC LABELING AND TARGETED DELIVERY OF PROTEINS FOR THE TREATMENT OF CANCER | ADVANCED PROTEOME THERAPEUTICS INC. | 2015-07-23 | — | — | US | disclosed |
| US-8877970-B2 | Inhibitors of carbonic anhydrase IX | MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) | 2014-11-04 | — | — | US | disclosed |
| US-4431848-A | Preparation of resorcinol and substituted resorcinols by liquid-phase dehydrogenation of 1,3-cyclic diones derived by vapor-phase cyclization of delta-keto carboxylic acid esters | KOPPERS COMPANY, INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4399310-A | Preparation of 1,3-cyclic diones by vapor phase cyclization of delta-keto carboxylic acid esters utilizing carrier condensable under ambient conditions | KOPPERS COMPANY, INC. (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0013254-B1 | PROCESS FOR THE PREPARATION OF 5-OXOHEXANOIC ACIDS, THEIR ESTERS AND NITRILES | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-08-04 | — | — | EP | disclosed |
| EP-0013254-A2 | Process for the preparation of 5-oxohexanoic acids, their esters and nitriles | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-07-09 | — | — | EP | disclosed |
| US-4072660-A | FROM A 4-OXO-CARBOXYLIC ACID ESTER OR DELTA-ENOL-LACTONE AND STRONG BASE IN GLYCOL DIALKYL ETHER SOLVENT | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-02-07 | — | — | US | disclosed |
| US-3950438-A | Preparation of resorcinol and alkyl-substituted derivatives thereof | STAMICARBON B.V. (NL) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150202314-A1 | SITE-SPECIFIC LABELING AND TARGETED DELIVERY OF PROTEINS FOR THE TREATMENT OF CANCER | KDR, VCAM1, FLT4 | TSHR 3148/4885SLC1A1 940/4885MGAM 3059/4885 |
| US-20160214097-A1 | CATALYST-CONTROLLED ALIPHATIC C-H OXIDATIONS | HMOX1, SOD3, CYC1 | TSHR 3813/4885SLC1A1 2966/4885MGAM 2319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.