Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1832529 | 0.97 | ALDH1A1 (0.37) | ALDH1A1TSHRGSRCPB2NFKB1 | |
| Hydrochloric Acid SCHEMBL1831383 | 0.95 | ALDH1A1 (0.35) | ALDH1A1TSHRGSRCPB2NFKB1 | |
| Bromide SCHEMBL1831768 | 0.95 | ALDH1A1 (0.35) | ALDH1A1TSHRGSRCPB2NFKB1 | |
| SCHEMBL2637711 | 0.90 | GSR (0.44) | ALDH1A1TSHRGSRCPB2NFKB1 | |
| Propanol SCHEMBL4460532 | 0.88 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| Bicarbonate SCHEMBL1829915 | 0.88 | GSR (0.45) | ALDH1A1TSHRGSRCPB2NFKB1 | |
| Bicarbonate SCHEMBL5155014 | 0.88 | GSR (0.45) | ALDH1A1TSHRGSRCPB2NFKB1 | |
| Bicarbonate SCHEMBL1832370 | 0.88 | GSR (0.45) | ALDH1A1TSHRGSRCPB2NFKB1 | |
| SCHEMBL3119564 | 0.86 | — | — | |
| SCHEMBL8175323 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328220-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2016-05-03 | — | — | US | disclosed |
| US-8992798-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2015-03-31 | — | — | US | disclosed |
| US-8784686-B2 | Liquids | INNOVIA FILMS LIMITED (GB) | 2014-07-22 | — | — | US | disclosed |
| US-20140187684-A1 | LIQUIDS | INNOVIA FILMS LIMITED (GB) | 2014-07-03 | — | — | US | disclosed |
| US-20110257433-A1 | LIQUIDS | THE UNIVERSITY OF YORK (GB) | 2011-10-20 | — | — | US | disclosed |
| EP-2322497-A1 | Ionic liquids comprising nitrogen containing cations | Innovia Films Limited (GB) | 2011-05-18 | — | — | EP | disclosed |
| US-20080221361-A1 | Ionic Liquids | BIONIQS LIMITED (GB) | 2008-09-11 | — | — | US | disclosed |
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | disclosed |