Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenylethyl Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylethyl Alcohol SCHEMBL28312218 | 0.91 | TDP1 (0.70) | TDP1ALDH1A1KEAP1SMN1; SMN2HDAC2 | |
| Phenylethyl Alcohol SCHEMBL28145944 | 0.91 | TDP1 (0.70) | TDP1ALDH1A1KEAP1SMN1; SMN2HDAC2 | |
| Phenylethyl Alcohol SCHEMBL28920276 | 0.89 | TDP1 (0.67) | TDP1ALDH1A1KEAP1SMN1; SMN2HDAC2 | |
| Phenylethyl Alcohol SCHEMBL10904935 | 0.87 | TDP1 (0.89) | TDP1ALDH1A1KEAP1SMN1; SMN2HDAC2 | |
| Acetic Acid SCHEMBL7431776 | 0.87 | ALDH1A1 (0.70) | TDP1ALDH1A1KEAP1SMN1; SMN2HDAC2 | |
| Phenylethyl Alcohol SCHEMBL1867158 | 0.87 | TDP1 (1.00) | TDP1ALDH1A1KEAP1SMN1; SMN2HDAC2 | |
| Phenylethyl Alcohol SCHEMBL8968173 | 0.87 | TDP1 (1.00) | TDP1ALDH1A1KEAP1SMN1; SMN2HDAC2 | |
| Phenylethyl Alcohol SCHEMBL1838 | 0.87 | — | — | |
| Acetophenone SCHEMBL8048362 | 0.87 | TDP1 (0.64) | TDP1ALDH1A1KEAP1SMN1; SMN2CYP4F2 | |
| Phenylethyl Alcohol SCHEMBL11450063 | 0.87 | TDP1 (1.00) | TDP1ALDH1A1KEAP1SMN1; SMN2HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111830145-B | Method for determining feeding ratio and distillation time of black-branch rose hydrosol | 北京市农林科学院 | 2022-11-11 | — | — | CN | claimed |
| CN-108853105-A | Cosmetic composition, composite medicine and food compositions | 西姆莱斯股份公司 | 2018-11-23 | — | — | CN | claimed |
| EP-1476534-B1 | \"DOUBLESSE\" METHOD FOR PRODUCING SPARKLING WINE | SEKTKELLEREI SCHLOSS WACHENHEI (DE) | 2005-06-29 | — | — | EP | claimed |
| WO-2001060986-A9 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN INC (US) | 2002-10-17 | — | — | WO | claimed |
| WO-2001060986-A2 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN, INC. (US) | 2001-08-23 | — | — | WO | claimed |
| CN-119677494-A | Flavored composition comprising at least one sulfur-containing antioxidant compound, at least one organic UV screening agent and at least one flavoring substance | 莱雅公司 | 2025-03-21 | — | — | CN | disclosed |
| EP-4330853-A1 | SYSTEMS AND METHODS FOR CHEMICAL AND BIOLOGICAL AUTHENTICATION | Salvus, LLC (US) | 2024-03-06 | — | — | EP | disclosed |
| EP-2646533-B2 | FABRIC CONDITIONERS | UNILEVER IP HOLDINGS B V (NL) | 2023-07-05 | — | — | EP | disclosed |
| EP-3310164-B1 | METHOD AND SYSTEM FOR ATTRACTING LEPIDOPTEROUS INSECTS | THE NEW ZEALAND INSTITUTE FOR PLANT AND FOOD RESEACH LTD (NZ) | 2023-06-07 | — | — | EP | disclosed |
| CN-115836061-A | Odorants and compositions comprising odorants | 丝趣科尔卡有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-110079466-B | Yeast and application thereof in fermentation of lotus seed wine | 中国石油大学(华东) | 2023-01-10 | — | — | CN | disclosed |
| CN-110079466-B | Yeast and application thereof in fermentation of lotus seed wine | 中国石油大学(华东) | 2023-01-10 | — | — | CN | disclosed |
| WO-2006133592-A1 | CYCLOAKYLIDENE- (ORTHO SUBSTITUTED PHENYL) -ACETONITRILES AND THEIR USE AS ODORANTS | GIVAUDAN SA (CH) | 2006-12-21 | — | — | WO | disclosed |
| CN-1144779-C | Process for preparing alkylphenylethyl aminopropanediol and intermediate obtained therein | 杭州中美华东制药有限公司 | 2004-04-07 | — | — | CN | disclosed |
| WO-2001060986-A9 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN INC (US) | 2002-10-17 | — | — | WO | disclosed |
| WO-2001060986-A2 | ESTERASE ENZYMES HAVING SELECTIVE ACTIVITY | THERMOGEN, INC. (US) | 2001-08-23 | — | — | WO | disclosed |
| EP-1115487-A1 | SUPPORTED BF3-COMPLEX SOLID ACID CATALYST, PREPARATION AND USE | THE UNIVERSITY OF YORK (GB) | 2001-07-18 | — | — | EP | disclosed |
| CN-1266844-A | Process for preparing alkylphenylethyl aminopropanediol and intermediate obtained therein | CHINA AMERICA JOINT HUADONG PH (CN) | 2000-09-20 | — | — | CN | disclosed |
| WO-2000013792-A1 | SUPPORTED BF3-COMPLEX SOLID ACID CATALYST, PREPARATION AND USE | THE UNIVERSITY OF YORK (GB) | 2000-03-16 | — | — | WO | disclosed |
| US-5552380-A | Perfume uses of phenyl alkanol derivatives | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1996-09-03 | — | — | US | disclosed |