Acetophenone

Acetophenone

SCHEMBL8048362

CC(=O)c1ccccc1.OCCc1ccccc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.64
LMNA P02545 1/20 0.60
KMT2A Q03164 2/20 0.54
ALDH1A1 P00352 3/20 0.53
MAOB P27338 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
CYP4F2 P78329 1/20 0.50
CYP4A11 Q02928 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MAPT P10636 1/20 0.50
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
CASP3 P42574 1/20 0.48
SENP8 Q96LD8 1/20 0.48
SENP7 Q9BQF6 1/20 0.48
SENP6 Q9GZR1 1/20 0.48
KEAP1 Q14145 1/20 0.47
HPGD P15428 3/20 0.46
KDM4E B2RXH2 1/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylethyl Alcohol SCHEMBL183529 0.87 TDP1 (0.76) TDP1LMNAALDH1A1SMN1; SMN2CYP4F2
SCHEMBL77965 0.85 KMT2A (0.64) TDP1LMNAKMT2AMAOBCYP4F2
Acetophenone SCHEMBL27986965 0.85 SMN1; SMN2 (0.60) TDP1LMNAKMT2AALDH1A1MAOB
Phenylethyl Alcohol SCHEMBL28145944 0.83 TDP1 (0.70) TDP1LMNAALDH1A1SMN1; SMN2CYP4F2
Benzoic Acid SCHEMBL22638831 0.83 TDP1 (0.70) TDP1ALDH1A1SMN1; SMN2CYP4F2CYP4A11
Phenylethyl Alcohol SCHEMBL28312218 0.83 TDP1 (0.70) TDP1LMNAKMT2AALDH1A1SMN1; SMN2
SCHEMBL2354530 0.83 LMNA (0.77) LMNAKMT2AALDH1A1MAOBSMN1; SMN2
Acetophenone SCHEMBL27579748 0.83 LMNA (0.64) LMNAKMT2AALDH1A1MAOBSMN1; SMN2
SCHEMBL12235066 0.82 CYP4F2 (0.67) TDP1LMNAALDH1A1MAOBCYP4F2
Phenylethyl Alcohol SCHEMBL28920276 0.82 TDP1 (0.67) TDP1LMNAALDH1A1SMN1; SMN2CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3890879-A1 HIGHLY ACTIVE AND HIGHLY SELECTIVE COPPER EXTRUDATE CATALYSTS BASF CORPORATION (US) 2021-10-13 EP disclosed
WO-2020117532-A1 HIGHLY ACTIVE AND HIGHLY SELECTIVE COPPER EXTRUDATE CATALYSTS BASF CORPORATION (US) 2020-06-11 WO disclosed
CN-110368946-A The method that carried non-crystal alloy catalysis hydrogenation of acetophenone prepares alpha-phenyl ethyl alcohol 青岛科技大学 2019-10-25 CN disclosed
CN-110357762-A A kind of preparation method of continuous production alpha-phenyl ethyl alcohol 中国科学院大连化学物理研究所 2019-10-22 CN disclosed
CN-110357762-A A kind of preparation method of continuous production alpha-phenyl ethyl alcohol 中国科学院大连化学物理研究所 2019-10-22 CN disclosed
CN-109939696-A A kind of Pt-Fe nanocatalyst, preparation method and application 中国科学技术大学 2019-06-28 CN disclosed
CN-106699507-A Preparation method for alpha-phenethanol 浙江医药高等专科学校 2017-05-24 CN disclosed
CN-101982482-B Method for preparing polyether amine by adopting amorphous alloy catalyst JIANGSU ZHONGSHAN CHEMICAL CO LTD 2013-01-30 CN disclosed
EP-0991401-A1 METHODS FOR CONTROLLING ENVIRONMENTAL ODORS ON THE BODY USING COMPOSITIONS COMPRISING UNCOMPLEXED CYCLODEXTRINS AND PERFUME THE PROCTER & GAMBLE COMPANY (US) 2000-04-12 EP disclosed
US-5861147-A APPLYING TO THE SKIN A COMPOSITION COMPRISING A WATER-SOLUBLE, UNCOMPLEXED CYCLODEXTRIN AND A HYDROPHILIC, VOLATILE PERFUME THE PROCTER & GAMBLE COMPANY (US) 1999-01-19 US disclosed
WO-1998056341-A1 METHODS FOR CONTROLLING ENVIRONMENTAL ODORS ON THE BODY USING COMPOSITIONS COMPRISING UNCOMPLEXED CYCLODEXTRINS AND PERFUME THE PROCTER & GAMBLE COMPANY (US) 1998-12-17 WO disclosed