⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18262 | 0.94 | — | — | |
| SCHEMBL17462 | 0.92 | USP2 (0.33) | — | |
| SCHEMBL14176589 | 0.92 | USP2 (0.33) | — | |
| SCHEMBL178384 | 0.88 | — | — | |
| SCHEMBL960157 | 0.81 | — | — | |
| SCHEMBL234016 | 0.81 | — | — | |
| SCHEMBL696343 | 0.78 | — | — | |
| SCHEMBL14223521 | 0.78 | — | — | |
| Acetic Acid SCHEMBL2478409 | 0.76 | FFAR3 (0.35) | — | |
| SCHEMBL321360 | 0.76 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024108010-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF PAIN AND INFLAMMATION | BAYER ANIMAL HEALTH GMBH (DE) | 2024-05-23 | — | — | WO | disclosed |
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DENTSPLY SIRONA INC. (US) | 2024-01-02 | — | — | US | disclosed |
| EP-4260909-A2 | SUBSTITUTED INDAZOLES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS | Bayer Pharma Aktiengesellschaft (DE) | 2023-10-18 | — | — | EP | disclosed |
| CN-109776510-B | N-substituted imidazole formate derivative and application thereof | 成都麻沸散医药科技有限公司 | 2023-08-18 | — | — | CN | disclosed |
| US-20230159563-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | ERASCA, INC. | 2023-05-25 | — | — | US | disclosed |
| CN-116120295-A | N-substituted imidazole formate derivative and application thereof | 成都麻沸散医药科技有限公司 | 2023-05-16 | — | — | CN | disclosed |
| US-11434205-B2 | Substituted imidazole carboxylate derivatives and the use thereof | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2022-09-06 | — | — | US | disclosed |
| EP-3747869-A1 | SUBSTITUTED IMIDAZOLE FORMATE DERIVATIVE AND USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2020-12-09 | — | — | EP | disclosed |
| US-20200369621-A1 | SUBSTITUTED IMIDAZOLECARBOXYLATE DERIVATIVES AND THE USE THEREOF | CHENGDU MFS PHARMA. CO., LTD. (CN) | 2020-11-26 | — | — | US | disclosed |
| WO-2019149228-A1 | SUBSTITUTED IMIDAZOLE FORMATE DERIVATIVE AND USE THEREOF | 成都安诺晨创医药科技有限公司 | 2019-08-08 | — | — | WO | disclosed |
| US-20050176800-A1 | Pyrrolidine derivatives as prostaglandin modulators | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2005-08-11 | — | — | US | disclosed |
| EP-1535896-A1 | PROCESS FOR PRODUCING CARBONIC ESTER | Asahi Kasei Chemicals Corporation (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-20040254233-A1 | Pyrazolidinone compounds as ligands of the prostaglandin ep2 and/or ep4 receptors | MERCK SERONO SA (CH) | 2004-12-16 | — | — | US | disclosed |
| EP-1458679-A2 | PYRROLIDINE DERIVATIVES AS PROSTAGLANDIN MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2004-09-22 | — | — | EP | disclosed |
| EP-1439837-A1 | PYRAZOLIDINONE COMPOUNDS AS LIGANDS OF THE PROSTAGLANDIN EP2 AND/OR EP4 RECEPTORS | Applied Research Systems ARS Holding N.V. (AN) | 2004-07-28 | — | — | EP | disclosed |
| WO-2003053923-A2 | PYRROLIDINE DERIVATIVES AS PROSTAGLANDIN MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-07-03 | — | — | WO | disclosed |
| WO-2003035064-A1 | PYRAZOLIDINONE COMPOUNDS AS LIGANDS OF THE PROSTAGLANDIN EP2 AND/OR EP4 RECEPTORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-05-01 | — | — | WO | disclosed |
| EP-0974580-B1 | Omega-cycloalkyl-prostaglandin E1 derivatives | ONO PHARMACEUTICAL CO (JP) | 2002-06-05 | — | — | EP | disclosed |
| US-6235780-B1 | ANTIHISTAMINE; VISION DEFECTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0974580-A1 | Omega-cycloalkyl-prostaglandin E1 derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-01-26 | — | — | EP | disclosed |