SCHEMBL178384

SCHEMBL178384

CCC1(CO)CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18353 0.88
SCHEMBL18262 0.88
Acetic Acid SCHEMBL2478409 0.87 FFAR3 (0.35)
SCHEMBL17462 0.85 USP2 (0.33)
SCHEMBL14176589 0.85 USP2 (0.33)
SCHEMBL2427203 0.81 EPHX1 (0.39)
SCHEMBL321360 0.81 KDM4E (0.30)
SCHEMBL15565885 0.81 KMT2A (0.35)
SCHEMBL2012671 0.79 VNN1 (0.33)
SCHEMBL798410 0.79 OPRM1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216516-A1 GLUTARIMIDE-CONTAINING KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF TIGER BIOTHERAPEUTICS INC. 2024-07-04 US disclosed
US-20240217972-A1 GLUTARIMIDE-CONTAINING PAN-KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF TIGER BIOTHERAPEUTICS INC. 2024-07-04 US disclosed
US-11873291-B2 Quinoline cGAS antagonist compounds IMMUNESENSOR THERAPEUTICS, INC. (US) 2024-01-16 US disclosed
US-20230365511-A1 Antiviral Pyrazolopiridinone Compounds NOVARTIS AG (CH) 2023-11-16 US disclosed
US-20230265075-A1 6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS AJAX THERAPEUTICS, INC. 2023-08-24 US disclosed
CN-109776510-B N-substituted imidazole formate derivative and application thereof 成都麻沸散医药科技有限公司 2023-08-18 CN disclosed
US-11691963-B2 6-heteroaryloxy benzimidazoles and azabenzimidazoles as JAK2 inhibitors AJAX THERAPEUTICS, INC. (US) 2023-07-04 US disclosed
US-20230159563-A1 TRICYCLIC PYRIDONES AND PYRIMIDONES ERASCA, INC. 2023-05-25 US disclosed
EP-3356344-B1 ISOINDOLINONE INHIBITORS OF THE MDM2-P53 INTERACTION HAVING ANTICANCER ACTIVITY ASTEX THERAPEUTICS LTD (GB) 2022-11-16 EP disclosed
US-20220306606-A1 MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR VERTEX PHARMACEUTICALS (SAN DIEGO) LLC 2022-09-29 US disclosed
EP-1760085-A1 PROCESS FOR PRODUCTION OF ALKYLTIN ALKOXIDES Asahi Kasei Chemicals Corporation (JP) 2007-03-07 EP disclosed
US-7157448-B2 Acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same LG LIFE SCIENCES LTD. (KR) 2007-01-02 US disclosed
US-20060287365-A1 Substituted arylpyrazoles ZOETIS LLC 2006-12-21 US disclosed
WO-2006134468-A1 SUBSTITUTED ARYLPYRAZOLES FOR USE AGAINST PARASITITES PFIZER LIMITED (GB) 2006-12-21 WO disclosed
CN-1839112-A Method for producing aromatic carbonate ASAHI CHEMICAL CORP (JP) 2006-09-27 CN disclosed
EP-1640357-A1 METHOD FOR PRODUCING AROMATIC CARBONATE Asahi Kasei Chemicals Corporation (JP) 2006-03-29 EP disclosed
US-20050240045-A1 Process for producing carbonic ester ASAHI KASEI KABUSHIKI KAISHA (JP) 2005-10-27 US disclosed
CN-1675163-A Process for producing carbonic ester ASAHI CHEMICAL IND (JP) 2005-09-28 CN disclosed
EP-1535896-A1 PROCESS FOR PRODUCING CARBONIC ESTER Asahi Kasei Chemicals Corporation (JP) 2005-06-01 EP disclosed
WO-1995026976-A1 CYCLOPROPYL BASED O- AND N- AND S-PROTECTING GROUPS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1995-10-12 WO disclosed