Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.39 |
| ▸ | SMOX | Q9NWM0 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | EIF2AK1 | Q9BQI3 | 5/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18353509 | 0.92 | KDM1A (0.42) | KDM1ARCOR1SMOXEIF2AK1ABL1 | |
| SCHEMBL16995675 | 0.88 | KDM1A (0.45) | KDM1ARCOR1SMOXCYP1A2CYP3A4 | |
| SCHEMBL18353610 | 0.82 | KDM1A (0.42) | KDM1ARCOR1SMOXL3MBTL1ABL1 | |
| SCHEMBL18353618 | 0.81 | MAPK1 (0.38) | KDM1ARCOR1SMOXL3MBTL1EIF2AK1 | |
| SCHEMBL18353508 | 0.81 | L3MBTL1 (0.44) | KDM1ARCOR1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL18353476 | 0.81 | KDM1A (0.43) | KDM1ARCOR1SMOXL3MBTL1EIF2AK1 | |
| SCHEMBL16995666 | 0.80 | KDM1A (0.48) | KDM1ARCOR1SMOXEIF2AK1ABL1 | |
| SCHEMBL18353522 | 0.80 | KDM1A (0.43) | KDM1ARCOR1SMOXL3MBTL1ABL1 | |
| SCHEMBL18353764 | 0.79 | KDM1A (0.41) | KDM1ARCOR1SMOXL3MBTL1KMT2A | |
| SCHEMBL18353525 | 0.79 | MAOA (0.44) | KDM1ARCOR1SMOXCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170001968-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170001968-A1 | AMINOTRIAZOLE- AND AMINOTETRAZOLE-BASED KDM1A INHIBITORS AS EPIGENETIC MODULATORS | KDM1A, KDM1B, KDM3A | KDM1A 1/4885RCOR1 488/4885SMOX 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.