Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | RXRA | P19793 | 3/20 | 0.53 |
| ▸ | RXRB | P28702 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | FABP1 | P07148 | 1/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 4/20 | 0.45 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046636 | 0.88 | MAPT (0.68) | MAPTSMN1; SMN2RXRARXRBKMO | |
| SCHEMBL7247750 | 0.86 | RXRA (0.66) | MAPTRXRARXRBPOLBCTDSP1 | |
| SCHEMBL30116316 | 0.83 | DHODH (0.66) | MAPTRXRARXRBPOLBCTDSP1 | |
| SCHEMBL4729014 | 0.82 | DHODH (0.65) | MAPTSMN1; SMN2RXRARXRBKMO | |
| Bicarbonate SCHEMBL27850297 | 0.81 | RXRA (0.63) | MAPTSMN1; SMN2RXRARXRBPOLB | |
| SCHEMBL7248274 | 0.80 | TSHR (0.55) | MAPTRXRARXRBPOLBCTDSP1 | |
| SCHEMBL27577941 | 0.80 | RXRA (0.49) | MAPTSMN1; SMN2RXRARXRBPOLB | |
| Acetophenone SCHEMBL28342406 | 0.79 | MAPT (0.75) | MAPTSMN1; SMN2CTDSP1KMODHODH | |
| SCHEMBL3787106 | 0.79 | MAPT (0.57) | MAPTSMN1; SMN2RXRARXRBKMO | |
| Hydrochloric Acid SCHEMBL27634975 | 0.79 | BRD4 (0.50) | MAPTRXRARXRBKMODHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180072672-A1 | BIPYRIDYL COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-03-15 | — | — | US | disclosed |
| US-9908852-B2 | Bipyridyl compound | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2018-03-06 | — | — | US | disclosed |
| US-20170001960-A1 | BIPYRIDYL COMPOUND | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170001960-A1 | BIPYRIDYL COMPOUND | CBR1, NR0B2, ERBB2 | MAPT 4692/4885SMN1; SMN2 3447/4885RXRA 304/4885 |
| US-20180072672-A1 | BIPYRIDYL COMPOUND | CBR1, NR0B2, ERBB2 | MAPT 4692/4885SMN1; SMN2 3447/4885RXRA 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.