Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 12/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18355109 | 0.91 | HCAR2 (0.43) | ATMACHEALOX15MAPTRAB9A | |
| SCHEMBL18355347 | 0.90 | ATM (0.46) | ATMACHEALOX15MAPTRAB9A | |
| SCHEMBL18354930 | 0.90 | HCAR2 (0.44) | ATMACHEALOX15MAPTRAB9A | |
| SCHEMBL18353205 | 0.89 | ATM (0.55) | ATMACHEMAPTRAB9ANPSR1 | |
| SCHEMBL18355257 | 0.88 | HCAR2 (0.43) | ATMACHEALOX15MAPTRAB9A | |
| SCHEMBL18354903 | 0.88 | ATM (0.53) | ATMACHEHCAR2 | |
| SCHEMBL18352664 | 0.86 | ATM (0.47) | ATMACHEALOX15MAPTRAB9A | |
| SCHEMBL18354873 | 0.85 | ATM (0.50) | ATMACHEMAPTRAB9ANPSR1 | |
| SCHEMBL18406543 | 0.84 | ATM (0.46) | ATMACHEALOX15MAPTRAB9A | |
| SCHEMBL18364397 | 0.84 | HCAR2 (0.44) | ATMALOX15MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170001953-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | Nguyen, Mark Quang (US) | 2017-01-05 | — | — | US | disclosed |
| US-20170001953-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | Nguyen, Mark Quang (US) | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170001953-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | FH, FPGS, APC | ATM 4406/4885ACHE 53/4885ALOX15 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.