Phenol

Phenol

SCHEMBL1835645

CCCCN(CCO)CCO.Oc1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 5/20 0.58
DRD3 P35462 5/20 0.58
OPRM1 P35372 4/20 0.58
OPRD1 P41143 4/20 0.58
OPRK1 P41145 4/20 0.58
ESR1 P03372 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
ICMT O60725 1/20 0.42
ALB P02768 1/20 0.42
KCNH2 Q12809 2/20 0.41
DRD1 P21728 1/20 0.41
DRD4 P21917 1/20 0.41
DRD5 P21918 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
GLA P06280 1/20 0.41
CA3 P07451 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL5874877 0.92 DRD2 (0.65) DRD2DRD3OPRM1OPRD1OPRK1
Phenol SCHEMBL28134716 0.92 DRD2 (0.65) DRD2DRD3OPRM1OPRD1OPRK1
Phenol SCHEMBL3952563 0.86 DRD2 (0.66) DRD2DRD3OPRM1OPRD1OPRK1
Trolamine SCHEMBL3893278 0.86 TDP1 (0.55) DRD2DRD3OPRM1OPRD1OPRK1
Phthalic Acid SCHEMBL1131705 0.81 ALDH1A1 (0.50) DRD2DRD3OPRM1OPRD1OPRK1
Benzoic Acid SCHEMBL1131222 0.81 DAO (0.47) DRD2DRD3OPRM1OPRD1OPRK1
SCHEMBL10256853 0.80 HSD17B10 (0.56) DRD2DRD3OPRM1OPRD1OPRK1
Phenol SCHEMBL8503480 0.80 ALDH1A1 (0.52) DRD2DRD3OPRM1OPRD1OPRK1
Phenol SCHEMBL27998904 0.80 ALDH1A1 (0.52) DRD2DRD3OPRM1OPRD1OPRK1
Phenol SCHEMBL5875080 0.80 DRD2 (0.62) DRD2DRD3OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US claimed
US-9328220-B2 Liquids INNOVIA FILMS LIMITED (GB) 2016-05-03 US disclosed
US-8992798-B2 Liquids INNOVIA FILMS LIMITED (GB) 2015-03-31 US disclosed
US-8784686-B2 Liquids INNOVIA FILMS LIMITED (GB) 2014-07-22 US disclosed
US-20140187684-A1 LIQUIDS INNOVIA FILMS LIMITED (GB) 2014-07-03 US disclosed
US-20110257433-A1 LIQUIDS THE UNIVERSITY OF YORK (GB) 2011-10-20 US disclosed
EP-2322497-A1 Ionic liquids comprising nitrogen containing cations Innovia Films Limited (GB) 2011-05-18 EP disclosed
CN-101316810-A Ionic liquids BIONIQS LTD (GB) 2008-12-03 CN disclosed
US-20080221361-A1 Ionic Liquids BIONIQS LIMITED (GB) 2008-09-11 US disclosed
US-20070185330-A1 Liquids THE UNIVERSITY OF YORK (GB) 2007-08-09 US disclosed