Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | NMT2 | O60551 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.33 |
| ▸ | MME | P08473 | 3/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 4/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.30 |
| ▸ | ECE1 | P42892 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18373241 | 0.89 | ALDH1A1 (0.40) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL11984206 | 0.89 | GABRR1 (0.47) | GABRR1NMT2NMT1GABBR2GABBR1 | |
| SCHEMBL18373242 | 0.86 | NMT2 (0.39) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL18357270 | 0.85 | ALDH1A1 (0.42) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL26169922 | 0.84 | GABRR1 (0.38) | ALDH1A1GABRR1GABBR2GABBR1MME | |
| SCHEMBL18357216 | 0.83 | NMT2 (0.39) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL16156107 | 0.83 | ALDH1A1 (0.49) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL17882016 | 0.81 | GABRR1 (0.42) | HSD17B10GABRR1MMESIRT6SIRT1 | |
| SCHEMBL18373247 | 0.78 | NMT1 (0.40) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL18373248 | 0.78 | ALDH1A1 (0.42) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872884-B1 | Pristinamycin compositions, LPXC compositions, their improvements, and combinations thereof | FLEURIR ABX LLC (US) | 2018-01-23 | — | — | US | disclosed |
| US-9539305-B1 | Pristinamycin compositions, LpxC compositions, their improvements, and combinations thereof | FLEURIR ABX LLC (US) | 2017-01-10 | — | — | US | disclosed |