Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.68 |
| ▸ | HTR5A | P47898 | 1/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.50 |
| ▸ | HTR2C | P28335 | 7/20 | 0.50 |
| ▸ | HTR2B | P41595 | 7/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.48 |
| ▸ | TMIGD3 | P0DMS9 | 5/20 | 0.48 |
| ▸ | TSPO | P30536 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20122107 | 1.00 | HRH2 (0.68) | HRH2HTR5AADORA1HTR2CHTR2B | |
| SCHEMBL21779299 | 1.00 | HRH2 (0.68) | HRH2HTR5AADORA1HTR2CHTR2B | |
| SCHEMBL16774095 | 1.00 | HRH2 (0.68) | HRH2HTR5AADORA1HTR2CHTR2B | |
| SCHEMBL14401404 | 0.92 | HRH2 (0.77) | HRH2HTR5AADORA1HTR2CHTR2B | |
| SCHEMBL24220655 | 0.92 | HRH2 (0.77) | HRH2HTR5AADORA1HTR2CHTR2B | |
| SCHEMBL18352583 | 0.88 | HRH2 (0.52) | HRH2HTR5AADORA1HTR2CHTR2B | |
| SCHEMBL20122139 | 0.88 | HRH2 (0.67) | HRH2HTR5AADORA1HTR2CHTR2B | |
| SCHEMBL16774081 | 0.88 | HRH2 (0.67) | HRH2HTR5AADORA1HTR2CHTR2B | |
| SCHEMBL22757376 | 0.85 | ADORA3 (0.56) | HRH2HTR5AADORA1HTR2CHTR2B | |
| SCHEMBL31350098 | 0.83 | HRH2 (0.81) | HRH2HTR5AADORA1HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170002007-A1 | A3 ADENOSINE RECEPTOR AGONISTS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170002007-A1 | A3 ADENOSINE RECEPTOR AGONISTS | ADORA3, ADORA2B, ADORA1 | HRH2 204/4885HTR5A 171/4885ADORA1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.