Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1832664 | 1.00 | OPRM1 (0.54) | OPRM1CHRM1OPRK1OPRL1USP2 | |
| SCHEMBL1838747 | 0.96 | OPRM1 (0.52) | OPRM1CHRM1OPRK1OPRL1USP2 | |
| SCHEMBL1835997 | 0.95 | OPRM1 (0.55) | OPRM1CHRM1OPRK1OPRL1USP2 | |
| SCHEMBL3806892 | 0.95 | OPRM1 (0.49) | OPRM1CHRM1OPRK1OPRL1USP2 | |
| SCHEMBL4895067 | 0.95 | OPRM1 (0.49) | OPRM1CHRM1OPRK1OPRL1USP2 | |
| SCHEMBL3670016 | 0.94 | OPRM1 (0.52) | OPRM1CHRM1OPRK1OPRL1USP2 | |
| SCHEMBL1834994 | 0.93 | OPRM1 (0.52) | OPRM1CHRM1OPRK1OPRL1USP2 | |
| SCHEMBL1835272 | 0.93 | OPRM1 (0.50) | OPRM1CHRM1OPRK1OPRL1CYP2D6 | |
| SCHEMBL3403017 | 0.93 | OPRM1 (0.50) | OPRM1CHRM1OPRK1OPRL1CYP2D6 | |
| SCHEMBL4682970 | 0.91 | CHRM1 (0.52) | OPRM1CHRM1OPRK1USP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160098-B9 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2011-05-18 | — | — | EP | claimed |
| EP-2160098-B1 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2010-11-10 | — | — | EP | claimed |