Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3806892 | 1.00 | OPRM1 (0.49) | OPRM1CHRM1USP2CYP1A2CYP2D6 | |
| SCHEMBL1832664 | 0.95 | OPRM1 (0.54) | OPRM1CHRM1USP2CYP1A2CYP2D6 | |
| SCHEMBL1835803 | 0.95 | OPRM1 (0.54) | OPRM1CHRM1USP2CYP1A2CYP2D6 | |
| SCHEMBL1835997 | 0.93 | OPRM1 (0.55) | OPRM1CHRM1USP2CYP1A2CYP2D6 | |
| SCHEMBL1838747 | 0.91 | OPRM1 (0.52) | OPRM1CHRM1USP2CYP1A2CYP2D6 | |
| SCHEMBL1833975 | 0.91 | OPRM1 (0.47) | OPRM1CHRM1CYP2D6TSHROPRK1 | |
| SCHEMBL1831703 | 0.91 | OPRM1 (0.47) | OPRM1CHRM1CYP2D6TSHROPRK1 | |
| SCHEMBL3400375 | 0.91 | OPRM1 (0.47) | OPRM1CHRM1CYP2D6TSHROPRK1 | |
| SCHEMBL3670016 | 0.90 | OPRM1 (0.52) | OPRM1CHRM1USP2CYP1A2CYP2D6 | |
| SCHEMBL1834994 | 0.88 | OPRM1 (0.52) | OPRM1CHRM1USP2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146172-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY, APPLICATIONS THEREOF TO THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY APICOMPLEXANS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2008-12-04 | — | — | WO | disclosed |