Uridine

Uridine

SCHEMBL1835845

N[C@@H](C(=O)P(=O)(O)OP(=O)(O)O)[C@@H](O)[C@@H](O)[C@H](O)CO.O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.58
SLC28A2 O43868 1/20 0.58
SLC29A1 Q99808 1/20 0.58
SLC28A3 Q9HAS3 1/20 0.58
P2RY2 P41231 11/20 0.58
P2RY6 Q15077 8/20 0.58
P2RY14 Q15391 7/20 0.53
P2RY4 P51582 4/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uridine SCHEMBL3684420 1.00 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL443385 0.92 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL1697430 0.92 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL8722666 0.91 SLC28A1 (0.59) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL2018331 0.88 P2RY2 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL3498449 0.87 SLC28A1 (0.55) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL4953755 0.86 SLC28A1 (0.54) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL3620601 0.86 SLC28A1 (0.54) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL1697431 0.86 SLC28A1 (0.54) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL11424489 0.84 P2RY2 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1534324-B1 TUMOR SPECIFIC OLIGOSACCHARIDE EPITOPES AND USE THEREOF GLYKOS FINLAND OY (FI) 2019-01-16 EP disclosed
US-20180055928-A1 Tumor specific oligosaccharide epitopes and use thereof GLYKOS FINLAND OY (FI) 2018-03-01 US disclosed
US-20140234318-A1 TUMOR SPECIFIC OLIGOSACCHARIDE EPITOPES AND USE THEREOF GLYKOS FINLAND OY (FI) 2014-08-21 US disclosed
US-8697061-B2 Tumor specific oligosaccharide epitopes and use thereof GLYKOS FINLAND OY (FI) 2014-04-15 US disclosed
EP-2322209-A2 Tumor specific oligosaccharide epitopes and use thereof Glykos Finland Oy (FI) 2011-05-18 EP disclosed
US-20060014672-A1 Tumor specific oligosaccharide epitopes and use thereof GLYKOS FINLAND OY (FI) 2006-01-19 US disclosed
EP-1534324-A2 TUMOR SPECIFIC OLIGOSACCHARIDE EPITOPES AND USE THEREOF BioTie Therapies Ltd. (FI) 2005-06-01 EP disclosed
WO-2004017810-A2 TUMOR SPECIFIC OLIGOSACCHARIDE EPITOPES AND USE THEREOF BIOTIE THERAPIES CORP. (FI) 2004-03-04 WO disclosed