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Uridine

Uridine

SCHEMBL3498449

O=C(CO)[C@@H](O)[C@H](O)[C@H](O)CO.O=C([C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)P(=O)(O)OP(=O)(O)O.O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.55

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ SLC28A1 O00337 1/20 0.55
▸ SLC28A2 O43868 1/20 0.55
▸ SLC29A1 Q99808 1/20 0.55
▸ SLC28A3 Q9HAS3 1/20 0.55
▸ P2RY2 P41231 11/20 0.54
▸ P2RY6 Q15077 10/20 0.54
▸ P2RY14 Q15391 7/20 0.53
▸ P2RY4 P51582 6/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uridine SCHEMBL443385 0.95 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL1697430 0.95 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL8722666 0.94 SLC28A1 (0.59) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL3620601 0.90 SLC28A1 (0.54) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL1835845 0.87 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL3684420 0.87 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine_Diphosphate SCHEMBL28280124 0.86 P2RY2 (0.70) P2RY2P2RY6P2RY14P2RY4
Uridine SCHEMBL4953755 0.84 SLC28A1 (0.54) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL1697431 0.84 SLC28A1 (0.54) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL11424489 0.81 P2RY2 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106795195-A Non-caloric sweetener and its synthesis method 康纳根有限公司 2017-05-31 — — CN disclosed
CN-106795547-A Non-caloric sweetener and synthetic method 康纳根有限公司 2017-05-31 — — CN disclosed
CN-106714578-A Non-caloric sweetener and its synthesis method 康纳根有限公司 2017-05-24 — — CN disclosed
CN-106715451-A Non-caloric sweetener and its synthesis method 康纳根有限公司 2017-05-24 — — CN disclosed
US-20100167040-A1 IDENTIFICATION OF A NOVEL TYPE OF SUCROSE SYNTHASE AND USE THEREOF IN FIBER MODIFICATION BAYER BIOSCIENCE N.V. (BE) 2010-07-01 — — US disclosed
CN-101495626-A Identification of a novel type of sucrose synthase and use thereof in fiber modification BAYER BIOSCIENCE NV (BE) 2009-07-29 — — CN disclosed
EP-2054511-A1 IDENTIFICATION OF A NOVEL TYPE OF SUCROSE SYNTHASE AND USE THEREOF IN FIBER MODIFICATION Commonwealth Scientific and Industrial Research Organization (AU) 2009-05-06 — — EP disclosed
WO-2008012058-A1 IDENTIFICATION OF A NOVEL TYPE OF SUCROSE SYNTHASE AND USE THEREOF IN FIBER MODIFICATION COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2008-01-31 — — WO disclosed