Uridine

Uridine

SCHEMBL443385

O=C([C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)P(=O)(O)OP(=O)(O)O.O=c1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.60
SLC28A2 O43868 1/20 0.60
SLC29A1 Q99808 1/20 0.60
SLC28A3 Q9HAS3 1/20 0.60
P2RY2 P41231 11/20 0.59
P2RY6 Q15077 8/20 0.59
P2RY14 Q15391 7/20 0.55
P2RY4 P51582 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uridine SCHEMBL1697430 1.00 SLC28A1 (0.60) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL8722666 0.99 SLC28A1 (0.59) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL3498449 0.95 SLC28A1 (0.55) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL3620601 0.94 SLC28A1 (0.54) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL1835845 0.92 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL3684420 0.92 SLC28A1 (0.58) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL4953755 0.88 SLC28A1 (0.54) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL1697431 0.88 SLC28A1 (0.54) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL11424489 0.85 P2RY2 (0.51) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2
Uridine SCHEMBL21295128 0.85 SLC28A1 (0.61) SLC28A1SLC28A2SLC29A1SLC28A3P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 844 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028668-A1 DETECTION OF BASE MODIFICATIONS BY ENHANCING ELECTRICAL CONTRAST IN NANOPORES RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2026-01-29 US claimed
US-20260022424-A1 NUCLEIC ACID METHYLATION PROFILING METHOD GUARDANT HEALTH INC (US) 2026-01-22 US claimed
US-20260015668-A1 COMPOSITION AND METHODS RELATED TO MODIFICATION OF 5 HYDROXYMETHYLCYTOSINE (5-hmC) THE UNIVERSITY OF CHICAGO (US) 2026-01-15 US claimed
EP-4655416-A1 NUCLEIC ACID METHYLATION PROFILING METHOD Guardant Health, Inc. (US) 2025-12-03 EP claimed
EP-4565717-A1 DETECTION OF BASE MODIFICATIONS BY ENHANCING ELECTRICAL CONTRAST IN NANOPORES Ramot at Tel-Aviv University Ltd. (IL) 2025-06-11 EP claimed
WO-2024159053-A1 NUCLEIC ACID METHYLATION PROFILING METHOD GUARDANT HEALTH, INC. (US) 2024-08-02 WO claimed
US-20240209430-A1 METHODS FOR THE AMPLIFICATION OF BISULFITE-TREATED DNA THE UNIVERSITY OF CHICAGO (US) 2024-06-27 US claimed
WO-2024028866-A1 DETECTION OF BASE MODIFICATIONS BY ENHANCING ELECTRICAL CONTRAST IN NANOPORES RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2024-02-08 WO claimed
US-20210310062-A1 METHODS FOR THE AMPLIFICATION OF BISULFITE-TREATED DNA THE UNIVERSITY OF CHICAGO (US) 2021-10-07 US claimed
US-11091793-B2 Detection of hydroxymethylcytosine bases RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2021-08-17 US claimed
CN-1291649-A Genetically engineered virus of Chinese ballworm WUHAN INST OF VIRUSES CHINESE (CN) 2001-04-18 CN claimed
EP-0763132-B1 ASSAY FOR ENZYME ACTIVITY USING A MICROFLUOROMETRIC ASSAY ISOLAB INC (US) 2001-01-24 EP claimed
CN-1258741-A Recombined Chinese bollworm virus WUHAN INST OF VIROLOGY ACADEMI (CN) 2000-07-05 CN claimed
CN-1208440-A Process for producing sugar nucleotides and complex carbohydrates KYOWA HAKKO KOGYO KK (JP) 1999-02-17 CN claimed
CN-1207135-A Process for producing sugar nucleotides and complex carbohydrates KYOWA HAKKO KOGYO KK (JP) 1999-02-03 CN claimed
EP-0870841-A1 PROCESSES FOR PRODUCING SUGAR NUCLEOTIDES AND COMPLEX CARBOHYDRATES KYOWA HAKKO KOGYO CO., LTD. (JP) 1998-10-14 EP claimed
EP-0763132-A4 ASSAY FOR ENZYME ACTIVITY USING A MICROFLUOROMETRIC ASSAY ISOLAB INC (US) 1997-06-18 EP claimed
EP-0763132-A1 ASSAY FOR ENZYME ACTIVITY USING A MICROFLUOROMETRIC ASSAY ISOLAB, INC. (US) 1997-03-19 EP claimed
US-5538857-A FLUORESCENCE ISOLAB, INC. (US) 1996-07-23 US claimed
WO-1995033072-A1 ASSAY FOR ENZYME ACTIVITY USING A MICROFLUOROMETRIC ASSAY ISOLAB, INC. (US) 1995-12-07 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015668-A1 COMPOSITION AND METHODS RELATED TO MODIFICATION OF 5 HYDROXYMETHYLCYTOSINE (5-hmC) MTAP, PNP, NT5C3B SLC28A1 269/4885SLC28A2 230/4885SLC29A1 183/4885
US-20260022424-A1 NUCLEIC ACID METHYLATION PROFILING METHOD DNMT3A, DNMT3L, DNMT1 SLC28A1 726/4885SLC28A2 381/4885SLC29A1 651/4885
US-20260028668-A1 DETECTION OF BASE MODIFICATIONS BY ENHANCING ELECTRICAL CONTRAST IN NANOPORES NCL, PCNA, DNMT1 SLC28A1 119/4885SLC28A2 113/4885SLC29A1 216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.