Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 4/20 | 0.34 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 3/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP4 | P49662 | 1/20 | 0.31 |
| ▸ | CASP5 | P51878 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL907630 | 0.78 | SUV39H2 (0.41) | PIK3CAKDM4EMAPT | |
| SCHEMBL907895 | 0.76 | CETP (0.42) | HRH4CASP1CASP4CASP5KDM4E | |
| SCHEMBL907899 | 0.76 | MPL (0.42) | MCHR1DRD2DRD4P2RY12MAPT | |
| SCHEMBL908229 | 0.72 | MTOR (0.39) | PIK3CADRD2HRH4DRD4AVPR1B | |
| SCHEMBL3878799 | 0.72 | DRD4 (0.40) | MCHR1DRD2HRH4DRD4KDM4E | |
| SCHEMBL907791 | 0.72 | P2RY12 (0.51) | P2RY12 | |
| SCHEMBL3880776 | 0.70 | HRH4 (0.39) | PIK3CAMCHR1HRH4 | |
| SCHEMBL3876390 | 0.70 | GALR2 (0.46) | — | |
| SCHEMBL907694 | 0.69 | CASP1 (0.40) | MCHR1HRH4CASP1CASP4CASP5 | |
| SCHEMBL908650 | 0.67 | SLC9A1 (0.37) | HRH4CASP1CASP4CASP5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786800-B1 | 1,4-Diarylpiperazine derivatives as capsaicin receptor modulators for treating pain | NEUROGEN CORP (US) | 2017-01-04 | — | — | EP | disclosed |