⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24178341 | 0.83 | — | — | |
| SCHEMBL20352358 | 0.79 | — | — | |
| SCHEMBL21185647 | 0.75 | — | — | |
| SCHEMBL16621969 | 0.75 | — | — | |
| SCHEMBL25779521 | 0.74 | — | — | |
| SCHEMBL19936352 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL19936347 | 0.72 | — | — | |
| SCHEMBL16372976 | 0.70 | — | — | |
| SCHEMBL13380197 | 0.70 | — | — | |
| SCHEMBL18923242 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873305-B2 | Processes for synthesis of substituted indole intermediates for the synthesis of serd compounds | GENENTECH, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-20220002304-A1 | PROCESSES FOR MAKING SERD TRICYCLIC COMPOUNDS HAVING A SUBSTITUTED PHENYL OR PYRIDINYL MOIETY | GENENTECH, INC. (US) | 2022-01-06 | — | — | US | disclosed |
| US-20170001983-A1 | TRPA1 MODULATORS | ALGOMEDIX, INC. | 2017-01-05 | — | — | US | disclosed |