SCHEMBL19936352

SCHEMBL19936352

C=C/C=C(N)\C(N)=C/C=C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TSHR P16473 1/20 0.35
FGFR4 P22455 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16621969 0.87
SCHEMBL18815190 0.84
SCHEMBL16543564 0.82
SCHEMBL18406035 0.79
SCHEMBL10056198 0.79
SCHEMBL19594684 0.79
SCHEMBL22114698 0.78
SCHEMBL24178341 0.77
SCHEMBL468227 0.77
SCHEMBL22828532 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018224-B2 Hydraulic fluid AFTON CHEMICAL CORPORATION (US) 2024-06-25 US disclosed
US-20230357535-A1 CROSSLINKABLE ELASTOMER COMPOSITION AND FLUORORUBBER MOLDED ARTICLE DAIKIN INDUSTRIES, LTD. (JP) 2023-11-09 US disclosed
US-11788026-B2 Hydraulic fluid AFTON CHEMICAL CORPORATION (US) 2023-10-17 US disclosed
US-20230055442-A1 HYDRAULIC FLUID AFTON CHEMICAL CORPORATION 2023-02-23 US disclosed
US-20230053321-A1 ONE-POT HOMOGENEOUS PROCESS FOR THE LARGE SCALE MANUFACTURE OF 2-SUBSTITUTED BENZIMIDAZOLES ECOLAB USA INC. (US) 2023-02-16 US disclosed
EP-4124646-A1 HYDRAULIC FLUID Afton Chemical Corporation (US) 2023-02-01 EP disclosed
WO-2023003468-A1 NOVEL INHIBITORS OF HISTONE DEACETYLASE (HDAC), AND METHODS, COMPOSITIONS AND USES RELATED THERETO. RIJKSUNIVERSITEIT GRONINGEN (NL) 2023-01-26 WO disclosed
US-11224224-B2 Thiobenzoimidazole as fungicides REDAG CROP PROTECTION LTD. (GB) 2022-01-18 US disclosed
US-20210317120-A1 NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM UNITED STATES GOVERNMENT 2021-10-14 US disclosed
US-11053203-B2 One-pot homogeneous process for the large scale manufacture of 2-substituted benzimidazoles ECOLAB USA INC. (US) 2021-07-06 US disclosed
US-10745403-B2 Compositions, uses and methods for making them Pimera, Inc. (US) 2020-08-18 US disclosed
US-20200181386-A1 FLUOROELASTOMER COMPOSITION AND MOLDED ARTICLE THEREOF TOKYO INSTITUTE OF TECHNOLOGY (JP) 2020-06-11 US disclosed
US-20200085053-A1 THIOBENZOIMIDAZOLE AS FUNGICIDES REDAG CROP PROT LTD (GB) 2020-03-19 US disclosed
US-20190144395-A1 NOVEL ONE-POT HOMOGENEOUS PROCESS FOR THE LARGE SCALE MANUFACTURE OF 2-SUBSTITUTED BENZIMIDAZOLES ECOLAB USA INC. (US) 2019-05-16 US disclosed
US-10000619-B2 Diaphragm DAIKIN INDUSTRIES, LTD. (JP) 2018-06-19 US disclosed
EP-2594555-B1 HETEROCYCLIC COMPOUND, AND p27 KIP1 DEGRADATION INHIBITOR ASKA PHARM CO LTD (JP) 2018-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190144395-A1 NOVEL ONE-POT HOMOGENEOUS PROCESS FOR THE LARGE SCALE MANUFACTURE OF 2-SUBSTITUTED BENZIMIDAZOLES TMBIM6, SMARCC1, SMARCC2 ALDH1A1 423/4885TSHR 3810/4885FGFR4 2706/4885
US-11224224-B2 Thiobenzoimidazole as fungicides CYP1B1, CYP51A1, CYP1A2 ALDH1A1 280/4885TSHR 979/4885FGFR4 1715/4885
US-20230053321-A1 ONE-POT HOMOGENEOUS PROCESS FOR THE LARGE SCALE MANUFACTURE OF 2-SUBSTITUTED BENZIMIDAZOLES SMARCC2, SMARCC1, PBRM1 ALDH1A1 336/4885TSHR 3463/4885FGFR4 2480/4885
US-11788026-B2 Hydraulic fluid OR10J3, OXSR1, NOX5 ALDH1A1 2187/4885TSHR 1466/4885FGFR4 568/4885
US-10745403-B2 Compositions, uses and methods for making them BAX, CASP3, BCL2 ALDH1A1 3165/4885TSHR 4870/4885FGFR4 4124/4885
US-11053203-B2 One-pot homogeneous process for the large scale manufacture of 2-substituted benzimidazoles TMBIM6, SMARCC1, PBRM1 ALDH1A1 366/4885TSHR 3501/4885FGFR4 2679/4885
US-20210317120-A1 NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM BAX, CASP3, CASP7 ALDH1A1 2282/4885TSHR 4584/4885FGFR4 1553/4885
US-20200085053-A1 THIOBENZOIMIDAZOLE AS FUNGICIDES CYP1B1, CYP51A1, CYP1A2 ALDH1A1 280/4885TSHR 979/4885FGFR4 1715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.