Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10624744 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL12169316 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL5567042 | 0.83 | ALDH1A1 (0.75) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL12362796 | 0.83 | ESR1 (0.49) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL16964220 | 0.83 | SIGMAR1 (0.54) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL3686095 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ACA2LMNA | |
| SCHEMBL19011453 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL17203236 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL8213969 | 0.81 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2ACA12CA9 | |
| SCHEMBL16964145 | 0.81 | CA1 (0.58) | ALDH1A1MEN1KMT2ACA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900638-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF MYCOBACTERIAL INFECTIONS | UNIVERSITÉ DE DROIT ET DE LA SANTÉ DE LILLE 2 (FR) | 2017-01-04 | — | — | EP | disclosed |