Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.75 |
| ▸ | CA12 | O43570 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1389312 | 1.00 | MGLL (0.75) | MGLLCA12CA1CA2CA9 | |
| SCHEMBL14907653 | 0.96 | MGLL (0.72) | MGLLCA12CA1CA2CA9 | |
| SCHEMBL14907652 | 0.94 | MGLL (0.67) | MGLLCA12CA1CA2CA9 | |
| SCHEMBL6200587 | 0.91 | MGLL (0.62) | MGLLCA12CA1CA2CA9 | |
| SCHEMBL14565135 | 0.89 | MGLL (0.86) | MGLLFAAHTRPV1BCL9CTNNB1 | |
| SCHEMBL11668314 | 0.89 | MGLL (0.86) | MGLLFAAHTRPV1BCL9CTNNB1 | |
| SCHEMBL27356591 | 0.89 | MGLL (0.62) | MGLLCA12CA1CA2CA9 | |
| SCHEMBL12651647 | 0.89 | MGLL (0.62) | MGLLCA12CA1CA2CA9 | |
| SCHEMBL12077169 | 0.89 | MGLL (0.60) | MGLLCA12CA1CA2CA9 | |
| SCHEMBL5362791 | 0.88 | MGLL (0.59) | MGLLCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017210246-A2 | PENICILLAMINE CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TARVEDA THERAPEUTICS, INC. (US) | 2017-12-07 | — | — | WO | disclosed |
| WO-2017003940-A1 | TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TARVEDA THERAPEUTICS, INC. (US) | 2017-01-05 | — | — | WO | disclosed |