Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.62 |
| ▸ | BCL9 | O00512 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228347 | 0.91 | BCL9 (0.59) | MGLLBCL9CTNNB1CA12CA1 | |
| SCHEMBL18359784 | 0.91 | MGLL (0.75) | MGLLBCL9CTNNB1CA12CA1 | |
| SCHEMBL1389312 | 0.91 | MGLL (0.75) | MGLLBCL9CTNNB1CA12CA1 | |
| SCHEMBL5362791 | 0.89 | MGLL (0.59) | MGLLBCL9CTNNB1CA12CA1 | |
| SCHEMBL21834877 | 0.87 | MGLL (0.53) | MGLLBCL9CTNNB1CA12CA1 | |
| SCHEMBL14907653 | 0.87 | MGLL (0.72) | MGLLBCL9CTNNB1CA12CA1 | |
| SCHEMBL13041080 | 0.85 | MGLL (0.52) | MGLLBCL9CTNNB1CA12CA1 | |
| SCHEMBL12077169 | 0.84 | MGLL (0.60) | MGLLBCL9CTNNB1CA12CA1 | |
| SCHEMBL7068808 | 0.84 | BCL9 (0.56) | MGLLBCL9CTNNB1MAPTKDM4E | |
| SCHEMBL14907652 | 0.84 | MGLL (0.67) | MGLLBCL9CTNNB1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165532-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-01-12 | — | — | EP | disclosed |
| US-6503897-B1 | N-Formylhydroxylamine derivatives; veterinary medicine; grampositive and gramnegative bacteria | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 2003-01-07 | — | — | US | disclosed |
| US-5552540-A | NONRADIOACTIVE LABELS | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 1996-09-03 | — | — | US | disclosed |
| EP-0366685-B1 | NUCLEOSIDE DERIVATIVES | FLOREY HOWARD INST (AU) | 1994-10-19 | — | — | EP | disclosed |
| EP-0366685-A4 | NUCLEOSIDE DERIVATIVES | — | 1991-03-20 | — | — | EP | disclosed |
| EP-0366685-A1 | NUCLEOSIDE DERIVATIVES. | FLOREY HOWARD INST (AU) | 1990-05-09 | — | — | EP | disclosed |
| WO-1988010264-A1 | NUCLEOSIDE DERIVATIVES | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY (AU) | 1988-12-29 | — | — | WO | disclosed |