SCHEMBL18360203

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12214541	0.85	CTSK (0.55)	CTSKCTSLCTSSCTSBCAPN1
	SCHEMBL18354713	0.84	MEN1 (0.46)	CTSKCTSLCTSSCTSBCAPN1
	SCHEMBL21675512	0.83	CTSK (0.61)	CTSKCTSLCTSSCTSBCAPN1
	SCHEMBL13519734	0.83	CTSK (0.52)	CTSKCTSLCTSSCTSBCAPN1
	SCHEMBL21561546	0.82	KMT2A (0.47)	CTSKCTSLCTSSCTSBMEN1
	SCHEMBL15374288	0.82	CYP1A2 (0.59)	CTSKCTSLCTSSCTSBCAPN1
	SCHEMBL9596442	0.82	CYP1A2 (0.59)	CTSKCTSLCTSSCTSBCAPN1
	SCHEMBL15107084	0.82	CYP1A2 (0.59)	CTSKCTSLCTSSCTSBCAPN1
	SCHEMBL15304537	0.82	MEN1 (0.52)	CTSKCTSSMEN1KMT2ANPSR1
	SCHEMBL27808938	0.82	CTSK (0.51)	CTSKCTSLCTSSCTSBCAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.