Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 15/20 | 0.42 |
| ▸ | KLK1 | P06870 | 5/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28375280 | 0.89 | KDM4C (0.53) | KLKB1KLK1KDM5AKDM2BKDM4C | |
| SCHEMBL16891444 | 0.87 | KLKB1 (0.42) | KLKB1KLK1KEAP1NFE2L2 | |
| SCHEMBL16880891 | 0.83 | KLKB1 (0.45) | KLKB1KLK1KEAP1NFE2L2 | |
| SCHEMBL16891625 | 0.82 | KLKB1 (0.45) | KLKB1KLK1KEAP1NFE2L2 | |
| SCHEMBL28375307 | 0.79 | KDM4C (0.54) | KLKB1KLK1KDM5AKDM2BKDM4C | |
| SCHEMBL16891515 | 0.76 | KLKB1 (0.52) | KLKB1KLK1 | |
| Propionic Acid SCHEMBL28105683 | 0.75 | KEAP1 (0.42) | KLKB1KLK1KEAP1NFE2L2 | |
| SCHEMBL18360055 | 0.75 | KLKB1 (0.51) | KLKB1KLK1 | |
| SCHEMBL18360327 | 0.74 | KLKB1 (0.42) | KLKB1KLK1 | |
| SCHEMBL16891553 | 0.74 | KLKB1 (0.49) | KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017001926-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC (BB) | 2017-01-05 | — | — | WO | disclosed |