Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 18/20 | 0.70 |
| ▸ | LOX | P28300 | 12/20 | 0.70 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18362019 | 0.93 | LOXL2 (0.71) | LOXL2LOX | |
| SCHEMBL18362036 | 0.85 | LOXL2 (0.73) | LOXL2LOX | |
| SCHEMBL18361783 | 0.83 | LOXL2 (0.64) | LOXL2LOX | |
| SCHEMBL18361791 | 0.83 | LOXL2 (0.98) | LOXL2LOXMAP2K7 | |
| Hydrochloric Acid SCHEMBL20337922 | 0.83 | LOXL2 (0.66) | LOXL2LOX | |
| SCHEMBL18361815 | 0.82 | LOXL2 (0.79) | LOXL2LOX | |
| SCHEMBL18049113 | 0.82 | LOXL2 (1.00) | LOXL2LOX | |
| Hydrochloric Acid SCHEMBL20337925 | 0.82 | LOXL2 (1.00) | LOXL2LOX | |
| SCHEMBL18362100 | 0.81 | LOXL2 (0.65) | LOXL2LOX | |
| SCHEMBL18361817 | 0.81 | LOXL2 (0.62) | LOXL2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180186755-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA INC (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180186755-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA INC (US) | 2018-07-05 | — | — | US | disclosed |
| WO-2017003862-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2017-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186755-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | LOXL2, LOXL1, LOX | LOXL2 1/4885LOX 3/4885KDR 2668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.