Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20337898 | 0.81 | HTR6 (0.48) | HTR6MCL1BCHE | |
| SCHEMBL18362160 | 0.81 | HTR6 (0.48) | HTR6MCL1PPARGPPARAPPARD | |
| SCHEMBL20655557 | 0.76 | HTR6 (0.46) | HTR6MCL1PPARGPPARAPPARD | |
| SCHEMBL20348538 | 0.76 | HTR2C (0.51) | HTR6MCL1 | |
| SCHEMBL18069184 | 0.75 | HTR6 (0.69) | HTR6MCL1PPARGPPARAPPARD | |
| SCHEMBL18362180 | 0.74 | HTR2C (0.60) | HTR6 | |
| SCHEMBL18361805 | 0.73 | PPARG (0.44) | MCL1PPARGPPARABADPPARD | |
| SCHEMBL18362172 | 0.73 | LOXL2 (0.42) | HTR6MCL1 | |
| SCHEMBL12542708 | 0.73 | HTR2C (0.58) | HTR6MCL1 | |
| SCHEMBL19089432 | 0.72 | RHEB (0.50) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017003862-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA, INC. (US) | 2017-01-05 | — | — | WO | disclosed |