SCHEMBL18363003

SCHEMBL18363003

CONc1c(C)csc1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
KMT2A Q03164 2/20 0.49
MAPT P10636 2/20 0.47
PKM P14618 1/20 0.47
ATM Q13315 1/20 0.47
POLB P06746 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2C19 P33261 1/20 0.43
HTR1A P08908 1/20 0.40
SCN1A P35498 1/20 0.40
SCN2A Q99250 1/20 0.40
SCN3A Q9NY46 1/20 0.40
KDM4E B2RXH2 2/20 0.39
GAA P10253 2/20 0.39
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18362869 0.86 MAPT (0.57) ALDH1A1KMT2AMAPTPKMATM
SCHEMBL4785611 0.79 ALDH1A1 (0.53) ALDH1A1KMT2AMAPTPKMATM
SCHEMBL11232857 0.76 ALDH1A1 (0.53) ALDH1A1KMT2AMAPTPKMATM
SCHEMBL6317855 0.75 ALDH1A1 (0.56) ALDH1A1KMT2AMAPTPKMATM
SCHEMBL18362849 0.73 MAPT (0.34) ALDH1A1KMT2AMAPTPKMATM
SCHEMBL7028014 0.72 CYP1A2 (0.47) ALDH1A1KMT2AMAPTPKMATM
SCHEMBL9098700 0.72 ALDH1A1 (0.53) ALDH1A1KMT2AMAPTPKMATM
SCHEMBL23295963 0.71 ALDH1A1 (0.52) ALDH1A1KMT2AMAPTPKMATM
SCHEMBL3715260 0.71 ALDH1A1 (0.52) ALDH1A1KMT2AMAPTPKMATM
Hydrochloric Acid SCHEMBL7035051 0.71 CYP1A2 (0.46) ALDH1A1KMT2AMAPTPKMATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2556062-B1 AMIDE DERIVATIVES OF AVENALUMIC ACID, PROCESS FOR PREPARING SAME AND COSMETIC COMPOSITIONS CONTAINING SAME PROD CHIM AUXILIAIRES ET DE SYNTHESE (FR) 2017-01-04 EP disclosed