SCHEMBL1836432

SCHEMBL1836432

CN(C)[C@](C)(C(=O)O)C(O)CCCN

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 5/20 0.39
ODC1 P11926 2/20 0.33
GSR P00390 1/20 0.33
ACACB O00763 1/20 0.33
ACACA Q13085 1/20 0.33
LMNA P02545 2/20 0.33
BLM P54132 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
RNPEP Q9H4A4 1/20 0.32
GABRR1 P24046 3/20 0.31
GABRR3 A8MPY1 1/20 0.30
GABRP O00591 1/20 0.30
GABRD O14764 1/20 0.30
HDAC3 O15379 1/20 0.30
GABBR2 O75899 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1518982 1.00 CPB2 (0.39) CPB2ODC1GSRACACBACACA
SCHEMBL5664168 0.82 CPB2 (0.39) CPB2ODC1GSRACACBACACA
SCHEMBL5664164 0.82 CPB2 (0.39) CPB2ODC1GSRACACBACACA
SCHEMBL28562438 0.76 CPB2 (0.42) CPB2ODC1GSRACACBACACA
SCHEMBL28562441 0.76 CPB2 (0.42) CPB2ODC1GSRACACBACACA
SCHEMBL27458705 0.75 TSHR (0.42) ACACBACACATSHR
SCHEMBL15173970 0.74 CPB2 (0.38) CPB2ODC1GSRLMNABLM
SCHEMBL7278614 0.74 CPB2 (0.38) CPB2ODC1GSRLMNABLM
SCHEMBL8146401 0.69 TSHR (0.43) CPB2GSRTSHR
SCHEMBL27913441 0.69 ALDH1A1 (0.36) ACACBACACATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250302964-A1 Topical Compositions and Methods for Treatment of Diabetic Neuropathies CROSS III WILLIAM H (US) 2025-10-02 US claimed
US-12329818-B2 Topical compositions and methods for treatment of diabetic neuropathies CROSS III WILLIAM H (US) 2025-06-17 US claimed
US-20190285632-A1 METABALOMICS AND VIRAL DIAGNOSTICS SUITE EXCISION BIOTHERAPEUTICS, INC. (US) 2019-09-19 US claimed
US-20190275154-A1 Topical Compositions and Methods for Treatment of Diabetic Neuropathies CROSS III WILLIAM H (US) 2019-09-12 US claimed
EP-3510148-A1 HIV CLINICAL PLAN Excision Biotherapeutics, Inc. (US) 2019-07-17 EP claimed
US-20190194652-A1 HIV CLINICAL PLAN EXCISION BIOTHERAPEUTICS, INC. (US) 2019-06-27 US claimed
EP-3465213-A1 METABALOMICS AND VIRAL DIAGNOSTICS SUITE Excision Biotherapeutics, Inc. (US) 2019-04-10 EP claimed
WO-2018049372-A1 HIV CLINICAL PLAN EXCISION BIOTHERAPEUTICS INC (US) 2018-03-15 WO claimed
WO-2017205460-A1 METABALOMICS AND VIRAL DIAGNOSTICS SUITE EXCISION BIOTHERAPEUTICS, INC. (US) 2017-11-30 WO claimed
US-20250302964-A1 Topical Compositions and Methods for Treatment of Diabetic Neuropathies CROSS III WILLIAM H (US) 2025-10-02 US disclosed
US-12329818-B2 Topical compositions and methods for treatment of diabetic neuropathies CROSS III WILLIAM H (US) 2025-06-17 US disclosed
US-12012634-B2 Methods for diagnosing, prognosing, and treating parkinson's disease or parkinsonism POPULATION BIO, INC. (US) 2024-06-18 US disclosed
CN-113793646-B Spectral image unmixing method based on weighted non-negative matrix factorization and application thereof 上海交通大学 2023-11-28 CN disclosed
US-20230020697-A1 METHODS AND COMPOSITIONS FOR DIAGNOSING, PROGNOSING, AND TREATING NEUROLOGICAL CONDITIONS POPULATION DIAGNOSTICS, INC. 2023-01-19 US disclosed
WO-2005083089-A1 GAMMA-BUTYROBETAINE HYDROXYLASE ORIGINATED FROM NEUROSPORA CRASSA CJ CORPORATION (KR) 2005-09-09 WO disclosed
US-5028538-A Stereospecific hydration of crotonobetaine SIGMA TAU INDUSTRIES FARMACEUTICHE RIUNITE S.P.A. (IT) 1991-07-02 US disclosed
EP-0244370-B1 PROCESS FOR PREPARING GAMMA BUTYROBETAINE Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1990-09-19 EP disclosed
US-4806282-A CATALYTIC HYDROGENATION OF CROTONOYLBETAINE CHLORIDE SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1989-02-21 US disclosed
EP-0244370-A2 Process for preparing gamma butyrobetaine Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1987-11-04 EP disclosed
US-4382092-A Pharmaceutical composition comprising gamma-butyrobetaine for the treatment of syndromes induced by L-carnitine deficiency SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) 1983-05-03 US disclosed