Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | SCD | O00767 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29022616 | 0.82 | CA1 (0.59) | CA12CA1CA2CA9CA14 | |
| SCHEMBL18375120 | 0.81 | POLB (0.50) | CA12CA1CA2CA9CA14 | |
| SCHEMBL4818576 | 0.80 | RAB9A (0.63) | CA12CA1CA2CA9CA14 | |
| SCHEMBL18754482 | 0.79 | ALDH1A1 (0.50) | CA12CA1CA2CA9CA14 | |
| SCHEMBL15501169 | 0.76 | HSD17B10 (0.58) | CA1CA2SMN1; SMN2KMT2AESR1 | |
| SCHEMBL17670798 | 0.75 | EPHX2 (0.59) | CA12CA1CA2CA9CA14 | |
| SCHEMBL22231444 | 0.75 | MAPT (0.54) | CA12CA1CA2CA9CA14 | |
| SCHEMBL18704333 | 0.75 | ATM (0.64) | CA12CA1CA2CA9CA14 | |
| SCHEMBL10567784 | 0.74 | CA1 (0.61) | CA12CA1CA2CA9CA14 | |
| SCHEMBL18364959 | 0.74 | CA12 (0.65) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170008927-A1 | ARTIFICIAL CATALYST SYSTEM SUBSTITUTABLE FOR IN VIVO ACYLATION FUNCTION | THE UNIVERSITY OF TOKYO (JP) | 2017-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008927-A1 | ARTIFICIAL CATALYST SYSTEM SUBSTITUTABLE FOR IN VIVO ACYLATION FUNCTION | KAT2A, KAT7, EP300 | CA12 1932/4885CA1 2128/4885CA2 2536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.