Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10498241 | 0.89 | HSD17B10 (0.40) | HSD17B10TDP1ALDH1A1GAAUSP2 | |
| SCHEMBL13500022 | 0.88 | HSD17B10 (0.48) | HSD17B10TDP1ALDH1A1GAAUSP2 | |
| SCHEMBL116747 | 0.88 | USP2 (0.53) | HSD17B10TDP1ALDH1A1GAAUSP2 | |
| SCHEMBL10498824 | 0.87 | USP2 (0.53) | HSD17B10TDP1ALDH1A1GAAUSP2 | |
| SCHEMBL3915203 | 0.84 | HSD17B10 (0.61) | HSD17B10TDP1ALDH1A1GAACA12 | |
| SCHEMBL23604400 | 0.84 | CA1 (0.53) | HSD17B10TDP1ALDH1A1GAAUSP2 | |
| SCHEMBL101404 | 0.83 | LMNA (0.50) | HSD17B10TDP1ALDH1A1GAAUSP2 | |
| SCHEMBL11219746 | 0.81 | USP2 (0.52) | HSD17B10TDP1USP2HTTLPAR5 | |
| SCHEMBL29044240 | 0.81 | USP2 (0.52) | HSD17B10TDP1USP2HTTLPAR5 | |
| SCHEMBL23072764 | 0.81 | KDM4E (0.39) | HSD17B10TDP1ALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8829229-B2 | Polyol ethers and process for making them | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-09-09 | — | — | US | disclosed |
| EP-2318346-B1 | POLYOL ETHERS AND PROCESS FOR MAKING THEM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-11-20 | — | — | EP | disclosed |
| WO-2011106194-A2 | PROCESS FOR MAKING POLYOL ETHERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-01 | — | — | WO | disclosed |
| US-20110207969-A1 | PROCESS FOR MAKING POLYOL ETHERS | DOW GLOBAL TECHNOLOGIES LLC | 2011-08-25 | — | — | US | disclosed |
| EP-2318346-A1 | POLYOL ETHERS AND PROCESS FOR MAKING THEM | Dow Global Technologies LLC (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010027663-A1 | POLYOL ETHERS AND PROCESS FOR MAKING THEM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-03-11 | — | — | WO | disclosed |
| US-20100048940-A1 | reductive etherification of a polyol with an aldehyde or ketone using a hydrogenation catalyt; resulting compounds have use as solvents, surfactants, degreasers, wetting agents, emulsifying agents, lubricants, and intermediates for surfactants; polyols can be from renewable raw materials | DOW GLOBAL TECHNOLOGIES LLC | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207969-A1 | PROCESS FOR MAKING POLYOL ETHERS | PUF60, PARG, PCBP1 | HSD17B10 727/4885TDP1 4209/4885ALDH1A1 3977/4885 |
| US-20100048940-A1 | reductive etherification of a polyol with an aldehyde or ketone using a hydrogenation catalyt; resulting compounds have use as solvents, surfactants, degreasers, wetting agents, emulsifying agents, lubricants, and intermediates for surfactants; polyols can be from renewable raw materials | RNF114, USP14, USP13 | HSD17B10 244/4885TDP1 1846/4885ALDH1A1 692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.