Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.37 |
| ▸ | NR1I3 | Q14994 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | TEK | Q02763 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1734285 | 0.96 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1NR1I3MEN1KMT2A | |
| SCHEMBL1733319 | 0.90 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1NR1I3NPC1RAB9A | |
| SCHEMBL12459953 | 0.87 | HSP90AA1 (0.39) | HSP90AA1HSP90AB1NR1I3MEN1KMT2A | |
| SCHEMBL12460588 | 0.81 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1MEN1KMT2ANPC1 | |
| SCHEMBL7607001 | 0.75 | TEK (0.41) | HSP90AA1HSP90AB1NR1I3NPC1RAB9A | |
| SCHEMBL1733715 | 0.74 | L3MBTL1 (0.43) | HSP90AA1HSP90AB1MEN1KMT2ANPC1 | |
| SCHEMBL512392 | 0.73 | JAK2 (0.36) | HSP90AB1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1733767 | 0.72 | PTGS2 (0.47) | MEN1KMT2ANPC1RAB9APTGS2 | |
| SCHEMBL1733352 | 0.70 | L3MBTL1 (0.45) | HSP90AA1HSP90AB1MEN1KMT2ANPC1 | |
| SCHEMBL1734193 | 0.69 | KLKB1 (0.47) | HSP90AA1HSP90AB1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051198-A2 | PYRIDINE DERIVATIVES AS AGRICULTURAL PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2011-05-05 | — | — | WO | disclosed |