Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 8/20 | 0.49 |
| ▸ | MAPK7 | Q13164 | 6/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | DCLK1 | O15075 | 5/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.40 |
| ▸ | AURKA | O14965 | 4/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | PIK3C2G | O75747 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | PLK4 | O00444 | 2/20 | 0.40 |
| ▸ | AURKC | Q9UQB9 | 2/20 | 0.40 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.40 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18369875 | 0.85 | BRD4 (0.64) | BRD4MAPK7KCNH2DCLK1LRRK2 | |
| SCHEMBL17059952 | 0.73 | MAPK7 (0.51) | BRD4MAPK7KCNH2DCLK1LRRK2 | |
| SCHEMBL18369924 | 0.72 | MAPK7 (0.59) | BRD4MAPK7KCNH2DCLK1LRRK2 | |
| SCHEMBL18370115 | 0.72 | DCLK1 (0.50) | BRD4MAPK7KCNH2DCLK1LRRK2 | |
| SCHEMBL17059911 | 0.72 | BRD4 (0.70) | BRD4MAPK7KCNH2DCLK1LRRK2 | |
| SCHEMBL18369796 | 0.72 | BRD4 (0.70) | BRD4MAPK7KCNH2DCLK1LRRK2 | |
| SCHEMBL18369897 | 0.71 | BRD4 (0.65) | BRD4MAPK7KCNH2DCLK1LRRK2 | |
| SCHEMBL18369886 | 0.71 | MAPK7 (0.57) | BRD4MAPK7KCNH2DCLK1LRRK2 | |
| SCHEMBL17059908 | 0.71 | MAPK7 (0.52) | BRD4MAPK7KCNH2DCLK1LRRK2 | |
| SCHEMBL18369861 | 0.71 | MAPK7 (0.53) | BRD4MAPK7KCNH2DCLK1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170008888-A1 | HETEROCYCLIC COMPOUNDS | ACTIVX BIOSCIENCES, INC. | 2017-01-12 | — | — | US | disclosed |
| US-20170008888-A1 | HETEROCYCLIC COMPOUNDS | ACTIVX BIOSCIENCES, INC. | 2017-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008888-A1 | HETEROCYCLIC COMPOUNDS | BET1, EP300, RBBP5 | BRD4 4/4885MAPK7 58/4885KCNH2 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.