SCHEMBL18372170

SCHEMBL18372170

CO[Si](C)(C)CCCNC(=O)NCCC[Si](OC)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 7/20 0.39
EPHX2 P34913 7/20 0.36
PRMT1 Q99873 1/20 0.34
LMNA P02545 1/20 0.33
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL254189 0.90 EPHX1 (0.46) EPHX1EPHX2PRMT1TSHR
SCHEMBL18372173 0.85 EPHX1 (0.39) EPHX1EPHX2PRMT1LMNATSHR
SCHEMBL14865799 0.85 EPHX1 (0.39) EPHX1EPHX2PRMT1TSHR
SCHEMBL19838191 0.84 EPHX1 (0.50) EPHX1EPHX2PRMT1LMNA
SCHEMBL28427817 0.83 EPHX1 (0.45) EPHX1EPHX2
SCHEMBL10557593 0.83 EPHX1 (0.57) EPHX1EPHX2LMNA
SCHEMBL13907618 0.83 EPHX1 (0.59) EPHX1EPHX2LMNA
SCHEMBL12190470 0.81 EPHX1 (0.39) EPHX1EPHX2PRMT1TSHR
SCHEMBL13950680 0.81 TSHR (0.52) EPHX1EPHX2LMNATSHR
SCHEMBL14519143 0.81 EPHX1 (0.39) EPHX1EPHX2PRMT1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10030193-B2 Consolidation compositions comprising multipodal silane coupling agents HALLIBURTON ENERGY SERVICES, INC. (US) 2018-07-24 US disclosed
US-20170009126-A1 Consolidation Compositions Comprising Multipodal Silane Coupling Agents HALLIBURTON ENERGY SERVICES, INC. (US) 2017-01-12 US disclosed