SCHEMBL14865799

SCHEMBL14865799

CO[Si](C)(CCCNC(=O)NCCC[Si](OC)(OC)OC)OC

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 7/20 0.39
PRMT1 Q99873 1/20 0.34
EPHX2 P34913 4/20 0.33
TSHR P16473 2/20 0.32
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16412053 0.92 EPHX1 (0.45) EPHX1PRMT1EPHX2TSHRPOLB
SCHEMBL254189 0.90 EPHX1 (0.46) EPHX1PRMT1EPHX2TSHRPOLB
SCHEMBL17133272 0.90 CA3 (0.33) EPHX1
SCHEMBL18372173 0.85 EPHX1 (0.39) EPHX1PRMT1EPHX2TSHRPOLB
SCHEMBL17133243 0.85 EPHX1 (0.57) EPHX1EPHX2
SCHEMBL12972152 0.85 EPHX1 (0.55) EPHX1EPHX2
SCHEMBL18372170 0.85 EPHX1 (0.39) EPHX1PRMT1EPHX2TSHR
SCHEMBL19838191 0.84 EPHX1 (0.50) EPHX1PRMT1EPHX2NPC1RAB9A
SCHEMBL12794858 0.84 EPHX1 (0.38) EPHX1PRMT1EPHX2TSHRPOLB
SCHEMBL17133244 0.83 KEAP1 (0.42) EPHX1EPHX2TSHRPOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3122328-B1 SILANE CONTAINING RESPECTIVELY AT LEAST TWO ALKOXY GROUPS AND A GUANIDONO OR CARBAMIDE GROUP EVONIK DEGUSSA GMBH (DE) 2019-05-01 EP disclosed
WO-2015144384-A1 SILANE CONTAINING RESPECTIVELY AT LEAST TWO ALKOXY GROUPS AND A GUANIDONO OR CARBAMIDE GROUP EVONIK DEGUSSA GMBH (DE) 2015-10-01 WO disclosed
US-9096776-B2 Silicone release coating composition of condensation reaction curing type SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-08-04 US disclosed
US-20130096257-A1 SILICONE RELEASE COATING COMPOSITION OF CONDENSATION REACTION CURING TYPE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-04-18 US disclosed