Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1842469 | 0.94 | NR1H4 (0.31) | NR1H4 | |
| SCHEMBL1840258 | 0.86 | NR1H4 (0.36) | NR1H4 | |
| SCHEMBL1836831 | 0.82 | NR1H4 (0.36) | NR1H4 | |
| SCHEMBL1840602 | 0.81 | NR1H4 (0.36) | NR1H4 | |
| SCHEMBL1843649 | 0.81 | NR1H4 (0.36) | NR1H4 | |
| SCHEMBL1841709 | 0.80 | NR1H4 (0.38) | NR1H4 | |
| SCHEMBL1838802 | 0.80 | NR1H4 (0.33) | NR1H4 | |
| SCHEMBL1840576 | 0.79 | NR1H4 (0.32) | NR1H4 | |
| SCHEMBL1838285 | 0.78 | NR1H4 (0.37) | NR1H4 | |
| SCHEMBL1841219 | 0.78 | NR1H4 (0.38) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321282-A1 | NEW BENZIMIDAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010028981-A1 | NEW BENZIMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-03-18 | — | — | WO | disclosed |