Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838802 | 0.99 | NR1H4 (0.33) | NR1H4 | |
| SCHEMBL1841221 | 0.96 | — | — | |
| SCHEMBL1840572 | 0.92 | — | — | |
| SCHEMBL1843296 | 0.91 | — | — | |
| SCHEMBL1841980 | 0.90 | NR1H4 (0.34) | NR1H4 | |
| SCHEMBL1843185 | 0.85 | — | — | |
| SCHEMBL1841925 | 0.84 | NR1H4 (0.47) | NR1H4 | |
| SCHEMBL1841802 | 0.84 | NR1H4 (0.33) | NR1H4 | |
| SCHEMBL1840349 | 0.83 | NR1H4 (0.40) | NR1H4 | |
| SCHEMBL1840308 | 0.82 | HSD11B1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321282-A1 | NEW BENZIMIDAZOLE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010028981-A1 | NEW BENZIMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-03-18 | — | — | WO | disclosed |