SCHEMBL183732

SCHEMBL183732

CC(C)(C)[Si](C)(C)Oc1cccc(-c2ccccn2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 4/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
PKM P14618 1/20 0.47
TGFBR1 P36897 1/20 0.42
DYRK1A Q13627 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP19A1 P11511 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
CYP2A6 P11509 1/20 0.39
HTR1A P08908 1/20 0.39
HTR7 P34969 1/20 0.39
LMNA P02545 2/20 0.39
HPGD P15428 2/20 0.39
MAPT P10636 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL183954 0.96 GRM5 (0.44) GRM5NPC1RAB9ASMN1; SMN2PKM
2-Phenylbenzo[D]Thiazole SCHEMBL17598955 0.83 RAB9A (0.52) NPC1RAB9ASMN1; SMN2PKMLMNA
SCHEMBL29496945 0.78 DYRK1A (0.66) GRM5NPC1RAB9ASMN1; SMN2PKM
SCHEMBL183897 0.78 DYRK1A (0.66) GRM5NPC1RAB9ASMN1; SMN2PKM
SCHEMBL12251030 0.78 BACE1 (0.50) GRM5NPC1RAB9ASMN1; SMN2PKM
SCHEMBL31187765 0.77 GRM5 (0.49) GRM5NPC1RAB9ASMN1; SMN2PKM
SCHEMBL17500184 0.77 GRM5 (0.49) GRM5NPC1RAB9ASMN1; SMN2PKM
SCHEMBL7706827 0.77 CA1 (0.50) SMN1; SMN2CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL22799655 0.77 CA12 (0.38) SMN1; SMN2LMNAMAPTMEN1GAA
SCHEMBL6831093 0.76 DYRK1A (0.64) GRM5NPC1RAB9ASMN1; SMN2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9290692-B2 Polymer light-emitting material, method for producing the same, and organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-22 US disclosed
US-9290692-B2 Polymer light-emitting material, method for producing the same, and organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-22 US disclosed
US-9290692-B2 Polymer light-emitting material, method for producing the same, and organic electroluminescent device NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2016-03-22 US disclosed
EP-2402413-B1 POLYMER LIGHT-EMITTING MATERIAL, METHOD FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEM CO (JP) 2015-07-22 EP disclosed
EP-2402413-A1 POLYMER LIGHT-EMITTING MATERIAL, METHOD FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel Chemical Co., Ltd. (JP) 2012-01-04 EP disclosed
EP-2402413-A1 POLYMER LIGHT-EMITTING MATERIAL, METHOD FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel Chemical Co., Ltd. (JP) 2012-01-04 EP disclosed
US-7763365-B2 Light emitting material and organic light-emitting device SHOWA DENKO K.K. (JP) 2010-07-27 US disclosed
US-7763365-B2 Light emitting material and organic light-emitting device SHOWA DENKO K.K. (JP) 2010-07-27 US disclosed
US-7736757-B2 Light emitting material and organic light-emitting device SHOWA DENKO K.K. (JP) 2010-06-15 US disclosed
US-7736757-B2 Light emitting material and organic light-emitting device SHOWA DENKO K.K. (JP) 2010-06-15 US disclosed
US-7396598-B2 Light emitting material and organic light-emitting device SHOWA DENKO K.K. (JP) 2008-07-08 US disclosed
US-7396598-B2 Light emitting material and organic light-emitting device SHOWA DENKO K.K. (JP) 2008-07-08 US disclosed
US-7396598-B2 Light emitting material and organic light-emitting device SHOWA DENKO K.K. (JP) 2008-07-08 US disclosed
US-20080152947-A1 LIGHT EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE SHOWA DENKO K.K. (JP) 2008-06-26 US disclosed
US-20080152947-A1 LIGHT EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE SHOWA DENKO K.K. (JP) 2008-06-26 US disclosed
US-20080152947-A1 LIGHT EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE SHOWA DENKO K.K. (JP) 2008-06-26 US disclosed
US-20040247934-A1 Light emitting material and organic light-emitting device SAMSUNG ELECTRONICS CO., LTD (KR) 2004-12-09 US disclosed
EP-1407501-A2 LIGHT EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE Showa Denko K.K. (JP) 2004-04-14 EP disclosed
WO-2003092334-A1 PHOSPHORESCENT POLYMER COMPOUND, LIGHT EMITTING MATERIAL AND ORGANIC ELECTROLUMINESCENT (EL) DEVICE USING THE COMPOUND NIPPON HOSO KYOKAI (JP) 2003-11-06 WO disclosed
WO-2003001616-A2 LIGHT EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE SHOWA DENKO K.K. (JP) 2003-01-03 WO disclosed