SCHEMBL18375484

SCHEMBL18375484

CN[C@@H](CCCCNC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)CC[C@H](NC(C)=O)C(=O)O)C(=O)O)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ALB P02768 3/20 0.56
▸ FOLH1 Q04609 2/20 0.56
▸ NOD1 Q9Y239 5/20 0.49
▸ GLP1R P43220 8/20 0.48
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ EPHX2 P34913 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14685805 0.92 ALB (0.52) ALBFOLH1NOD1GLP1RSMN1; SMN2
SCHEMBL17359223 0.92 ALB (0.52) ALBFOLH1NOD1GLP1RSMN1; SMN2
SCHEMBL18710730 0.92 ALB (0.56) ALBFOLH1NOD1GLP1RSMN1; SMN2
SCHEMBL14118034 0.89 FOLH1 (0.51) ALBFOLH1NOD1GLP1R
SCHEMBL20122043 0.88 ALB (0.58) ALBFOLH1NOD1GLP1RSMN1; SMN2
SCHEMBL12964947 0.88 ALB (0.55) ALBFOLH1NOD1GLP1RSMN1; SMN2
SCHEMBL14118103 0.88 NOD1 (0.50) ALBFOLH1NOD1GLP1REPHX2
SCHEMBL24174150 0.87 GLP1R (0.57) ALBFOLH1NOD1GLP1REPHX2
SCHEMBL15507483 0.87 GLP1R (0.57) ALBFOLH1NOD1GLP1REPHX2
SCHEMBL15002709 0.87 GLP1R (0.57) ALBFOLH1NOD1GLP1REPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170008943-A1 STABLE GLUCAGON ANALOGUES AND USE FOR TREATMENT OF HYPOGLYCAEMIA NOVO NORDISK A/S (DK) 2017-01-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170008943-A1 STABLE GLUCAGON ANALOGUES AND USE FOR TREATMENT OF HYPOGLYCAEMIA GLP1R, IAPP, GCG ALB 2102/4885FOLH1 1307/4885NOD1 476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback