SCHEMBL17359223

SCHEMBL17359223

CN[C@@H](CCCCNC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)CC[C@H](NC(=O)CC[C@H](NC(C)=O)C(=O)O)C(=O)O)C(=O)O)C(=O)O)C(N)=O

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ALB P02768 3/20 0.52
▸ FOLH1 Q04609 1/20 0.51
▸ NOD1 Q9Y239 5/20 0.48
▸ SIRT5 Q9NXA8 2/20 0.47
▸ GLP1R P43220 8/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14685805 1.00 ALB (0.52) ALBFOLH1NOD1SIRT5GLP1R
SCHEMBL18375484 0.92 ALB (0.56) ALBFOLH1NOD1GLP1RSMN1; SMN2
SCHEMBL18710730 0.90 ALB (0.56) ALBFOLH1NOD1SIRT5GLP1R
SCHEMBL13857598 0.90 ALB (0.55) ALBFOLH1NOD1SIRT5GLP1R
SCHEMBL18088436 0.88 NOD1 (0.54) FOLH1NOD1GLP1R
SCHEMBL24795872 0.87 NOD1 (0.65) NOD1GLP1R
SCHEMBL13812422 0.86 NOD1 (0.54) ALBFOLH1NOD1SIRT5GLP1R
SCHEMBL24383258 0.86 ALB (0.47) ALBFOLH1NOD1SIRT5GLP1R
SCHEMBL13857596 0.85 ALB (0.51) ALBFOLH1NOD1SIRT5GLP1R
SCHEMBL21937059 0.84 FOLH1 (0.49) ALBFOLH1NOD1GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170008943-A1 STABLE GLUCAGON ANALOGUES AND USE FOR TREATMENT OF HYPOGLYCAEMIA NOVO NORDISK A/S (DK) 2017-01-12 — — US disclosed
US-20150368313-A1 Novel Glucagon Analogues NOVO NORDISK AS (DK) 2015-12-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170008943-A1 STABLE GLUCAGON ANALOGUES AND USE FOR TREATMENT OF HYPOGLYCAEMIA GLP1R, IAPP, GCG ALB 2102/4885FOLH1 1307/4885NOD1 476/4885
US-20150368313-A1 Novel Glucagon Analogues GLP1R, GCG, IAPP ALB 2451/4885FOLH1 247/4885NOD1 1052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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