SCHEMBL18376239

SCHEMBL18376239

COC(=O)CCNC(=O)CCl

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.52
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CA12 O43570 4/20 0.48
CA14 Q9ULX7 4/20 0.48
EPHX2 P34913 1/20 0.44
RECQL P46063 1/20 0.43
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
CA7 P43166 2/20 0.39
CA9 Q16790 2/20 0.39
LMNA P02545 2/20 0.39
KDM4E B2RXH2 1/20 0.39
FAAH O00519 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CA2 P00918 1/20 0.38
HTT P42858 2/20 0.38
MAPT P10636 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22500103 0.84 ALDH1A1 (0.65) TSHRALDH1A1SMN1; SMN2EPHX2RECQL
SCHEMBL1709284 0.82 MEN1 (0.56) TSHRCA12CA14EPHX2RECQL
SCHEMBL4432951 0.81 GAA (0.48) ALDH1A1SMN1; SMN2KMT2AFAAHL3MBTL1
SCHEMBL2839890 0.80 TSHR (0.50) TSHRALDH1A1CA12CA14EPHX2
SCHEMBL22345533 0.80 TSHR (0.50) TSHRALDH1A1CA12CA14EPHX2
SCHEMBL18404145 0.80 LMNA (0.52) TSHRALDH1A1CA12CA14EPHX2
SCHEMBL5839443 0.80 TSHR (0.52) TSHRALDH1A1CA12CA14EPHX2
SCHEMBL14902247 0.80 MGAM (0.52) TSHRALDH1A1CA12CA14EPHX2
SCHEMBL5317737 0.79 RECQL (0.61) TSHRALDH1A1SMN1; SMN2EPHX2RECQL
SCHEMBL31070310 0.78 TSHR (0.54) TSHRALDH1A1CA12CA14RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017005822-A1 FUNCTIONALIZABLE MOLECULAR PROBE FOR X-RAY FLUORESCENCE IMAGING AND MULTIMODAL IMAGING PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) 2017-01-12 WO disclosed