Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.56 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22560078 | 0.86 | CYP3A4 (0.66) | TSHRRECQLHPGDMAPK14GAA | |
| SCHEMBL7353744 | 0.85 | GAA (0.75) | TSHRRECQLHPGDTPSAB1GAA | |
| SCHEMBL29531512 | 0.84 | EPHX2 (0.67) | HPGDMAPK14GAAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL1128739 | 0.83 | GAA (0.72) | TSHRRECQLHPGDTPSAB1GAA | |
| SCHEMBL14944099 | 0.83 | MAPK14 (0.61) | TSHRRECQLHPGDMAPK14ALDH1A1 | |
| SCHEMBL13192876 | 0.83 | HPGD (0.62) | TSHRRECQLHPGDMAPK14GAA | |
| SCHEMBL13192880 | 0.83 | RNF4 (0.62) | TSHRRECQLHPGDMAPK14GAA | |
| SCHEMBL10133183 | 0.83 | NPC1 (0.75) | TSHRRECQLHPGDMAPK14GAA | |
| SCHEMBL8935458 | 0.82 | GAA (0.66) | TPSAB1GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL27593863 | 0.82 | HPGD (0.61) | RECQLHPGDMAPK14GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170007588-A1 | SMALL MOLECULE INHIBITORS OF XBP1 SPLICING | GEORGETOWN UNIVERSITY (US) | 2017-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170007588-A1 | SMALL MOLECULE INHIBITORS OF XBP1 SPLICING | XBP1, RBM17, ERN2 | TSHR 3205/4885RECQL 2201/4885HPGD 3265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.