Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.61 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.59 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7353744 | 0.93 | GAA (0.75) | GAATRPV1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL1128739 | 0.91 | GAA (0.72) | GAATRPV1MEN1KMT2AALDH1A1 | |
| SCHEMBL1661081 | 0.85 | TRPV1 (0.76) | GAATRPV1MEN1KMT2ALMNA | |
| SCHEMBL8935389 | 0.84 | LMNA (0.67) | GAATRPV1LMNAALDH1A1HDAC3 | |
| SCHEMBL4436696 | 0.84 | GAA (0.79) | GAATRPV1MEN1KMT2ALMNA | |
| SCHEMBL8499126 | 0.83 | MEN1 (0.80) | GAATRPV1MEN1KMT2ALMNA | |
| SCHEMBL3825861 | 0.82 | HDAC3 (0.68) | TRPV1LMNAALDH1A1L3MBTL1HDAC3 | |
| SCHEMBL3435489 | 0.82 | TRPV1 (0.84) | GAATRPV1MEN1KMT2ALMNA | |
| SCHEMBL18376355 | 0.82 | TSHR (0.59) | GAAMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8792470 | 0.81 | ALDH1A1 (0.71) | GAATRPV1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |