SCHEMBL18379065

SCHEMBL18379065

CCCCCCCCCCCCN1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(Cc1ccc(N2CCCCC2)cc1)C5=O

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 6/20 0.51
▸ STAT3 P40763 1/20 0.45
▸ HIF1A Q16665 1/20 0.45
▸ MEN1 O00255 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ L3MBTL1 Q9Y468 2/20 0.45
▸ MAPK1 P28482 1/20 0.45
▸ RAB9A P51151 1/20 0.45
▸ ALDH1A1 P00352 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ ADRA1D P25100 7/20 0.43
▸ ADRA1A P35348 7/20 0.43
▸ ADRA1B P35368 7/20 0.43
▸ HTR1A P08908 3/20 0.41
▸ DRD2 P14416 1/20 0.41
▸ HTR2A P28223 1/20 0.41
▸ HTR6 P50406 1/20 0.41
▸ KDM4E B2RXH2 1/20 0.40
▸ GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18379170 0.92 HDAC6 (0.46) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL18379138 0.89 TERT (0.53) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL18379080 0.88 TERT (0.47) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL18379071 0.87 TERT (0.57) TERTMEN1KMT2AL3MBTL1MAPK1
SCHEMBL23425474 0.86 TERT (0.40) TERTMEN1KMT2AL3MBTL1MAPK1
SCHEMBL18379167 0.81 STAT3 (0.54) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL23957079 0.81 STAT3 (0.48) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL18379077 0.81 TERT (0.49) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL18379137 0.81 STAT3 (0.65) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL8071104 0.81 STAT3 (0.65) TERTSTAT3HIF1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200354356-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES UNIVERSITY OF UTAH 2020-11-12 — — US disclosed
US-20180201612-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES UNIVERSITY OF UTAH 2018-07-19 — — US disclosed
US-20180201612-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES UNIVERSITY OF UTAH 2018-07-19 — — US disclosed
WO-2017142609-A2 CHEMICAL SELF-DOPING OF ONE-DIMENSIONAL ORGANIC NANOMATERIALS FOR HIGH CONDUCTIVITY APPLICATION IN CHEMIRESISTIVE SENSING GAS OR VAPOR UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2017-08-24 — — WO disclosed
US-20170160252-A1 CHEMICAL SELF-DOPING OF ONE-DIMENSIONAL ORGANIC NANOMATERIALS FOR HIGH CONDUCTIVITY APPLICATION IN CHEMIRSISTIVE SENSING GAS OR VAPOR UNIVERSITY OF UTAH 2017-06-08 — — US disclosed
US-20170160252-A1 CHEMICAL SELF-DOPING OF ONE-DIMENSIONAL ORGANIC NANOMATERIALS FOR HIGH CONDUCTIVITY APPLICATION IN CHEMIRSISTIVE SENSING GAS OR VAPOR UNIVERSITY OF UTAH 2017-06-08 — — US disclosed
WO-2017008074-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2017-01-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354356-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES NCS1, DAXX, CNDP2 TERT 3724/4885STAT3 4101/4885HIF1A 3544/4885
US-20170160252-A1 CHEMICAL SELF-DOPING OF ONE-DIMENSIONAL ORGANIC NANOMATERIALS FOR HIGH CONDUCTIVITY APPLICATION IN CHEMIRSISTIVE SENSING GAS OR VAPOR DRD1, DRD4, DNER TERT 806/4885STAT3 1719/4885HIF1A 1831/4885
US-20180201612-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES NCS1, DAXX, CNDP2 TERT 3724/4885STAT3 4101/4885HIF1A 3544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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