Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 14/20 | 0.67 |
| ▸ | NFE2L2 | Q16236 | 14/20 | 0.67 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22206166 | 0.78 | NPC1 (0.55) | KEAP1NFE2L2CASP3SENP8SENP7 | |
| SCHEMBL29838394 | 0.78 | NPC1 (0.55) | KEAP1NFE2L2CASP3SENP8SENP7 | |
| SCHEMBL34467117 | 0.75 | KEAP1 (1.00) | KEAP1NFE2L2CASP3SENP8SENP7 | |
| SCHEMBL28605137 | 0.73 | MEN1 (0.65) | KEAP1NFE2L2CASP3SENP8SENP7 | |
| SCHEMBL27088373 | 0.71 | KEAP1 (0.62) | KEAP1NFE2L2CASP3SENP8SENP7 | |
| SCHEMBL27088356 | 0.71 | KEAP1 (0.62) | KEAP1NFE2L2CASP3SENP8SENP7 | |
| SCHEMBL30914344 | 0.71 | MAPT (0.63) | KEAP1NFE2L2MAPK1NPC1ALDH1A1 | |
| SCHEMBL929507 | 0.71 | MAPT (0.63) | KEAP1NFE2L2MAPK1NPC1ALDH1A1 | |
| SCHEMBL27984026 | 0.70 | MEN1 (0.61) | KEAP1NFE2L2MEN1KMT2ANPC1 | |
| SCHEMBL29838492 | 0.70 | ALDH1A1 (0.56) | KEAP1NFE2L2CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017005822-A1 | FUNCTIONALIZABLE MOLECULAR PROBE FOR X-RAY FLUORESCENCE IMAGING AND MULTIMODAL IMAGING | PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) | 2017-01-12 | — | — | WO | disclosed |