SCHEMBL1838565

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10976813	0.96	TSHR (0.44)	TSHRLTA4HCYP3A4TDP1RIPK1
	SCHEMBL1840257	0.89	LTA4H (0.50)	TSHRLTA4HRIPK1LMNAGAA
	SCHEMBL1840334	0.87	HTR2A (0.45)	CYP3A4TDP1RIPK1LMNAKMT2A
	SCHEMBL101880	0.85	CYP3A4 (0.50)	TSHRLTA4HCYP3A4TDP1GAA
	SCHEMBL16449662	0.83	CYP3A4 (0.41)	TSHRLTA4HCYP3A4TDP1LMNA
	SCHEMBL6714342	0.83	MAOB (0.56)	CYP3A4RIPK1GAAKMT2AALDH1A1
	SCHEMBL1836758	0.83	ALDH1A1 (0.39)	TSHRLTA4HRIPK1LMNAKMT2A
	SCHEMBL17674561	0.83	CYP3A4 (0.48)	TSHRLTA4HCYP3A4TDP1GAA
	SCHEMBL31153795	0.83	CYP3A4 (0.48)	TSHRLTA4HCYP3A4TDP1GAA
	SCHEMBL31059892	0.83	CYP3A4 (0.48)	TSHRLTA4HCYP3A4TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.