Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 2/20 | 0.38 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16622784 | 0.95 | L3MBTL1 (0.58) | KDM4EL3MBTL1ATMHDAC4TSPO | |
| SCHEMBL25817136 | 0.93 | KDM4E (0.60) | KDM4EL3MBTL1ATMHDAC4TSPO | |
| SCHEMBL9912829 | 0.91 | KDM4E (0.59) | KDM4EL3MBTL1ATMHDAC4TSPO | |
| SCHEMBL20633769 | 0.89 | KDM4E (0.61) | KDM4EL3MBTL1ATMHDAC4TSPO | |
| SCHEMBL20707516 | 0.88 | L3MBTL1 (0.61) | KDM4EL3MBTL1ATMHDAC4TSPO | |
| SCHEMBL20707473 | 0.88 | L3MBTL1 (0.67) | KDM4EL3MBTL1ATMHDAC4TSPO | |
| SCHEMBL18623502 | 0.88 | L3MBTL1 (0.61) | KDM4EL3MBTL1ATMHDAC4TSPO | |
| SCHEMBL20614656 | 0.88 | L3MBTL1 (0.61) | KDM4EL3MBTL1ATMHDAC4TSPO | |
| SCHEMBL20763400 | 0.88 | KDM4E (0.55) | KDM4EL3MBTL1ATMHDAC4TSPO | |
| SCHEMBL17206540 | 0.88 | L3MBTL1 (0.61) | KDM4EL3MBTL1ATMHDAC4TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170244049-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-08-24 | — | — | US | disclosed |
| WO-2017011531-A2 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2017-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170244049-A1 | ORGANIC LIGHT-EMITTING DIODE MATERIALS | CYBA, DDT, DRD1 | KDM4E 2858/4885L3MBTL1 24/4885ATM 1981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.