SCHEMBL25817136

SCHEMBL25817136

Nn1c2ccccc2c2cc(-c3ccc4c(c3)c3ccccc3n4-c3ccccc3)ccc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.60
▸ L3MBTL1 Q9Y468 2/20 0.60
▸ ATM Q13315 1/20 0.60
▸ IL1R1 P14778 1/20 0.42
▸ KMT2A Q03164 3/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ MAPT P10636 2/20 0.41
▸ HTT P42858 2/20 0.41
▸ PTGER4 P35408 1/20 0.39
▸ TSPO P30536 1/20 0.38
▸ HDAC4 P56524 1/20 0.38
▸ MAPK8 P45983 2/20 0.36
▸ MAPK1 P28482 2/20 0.35
▸ HPGD P15428 1/20 0.35
▸ HBB P68871 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ PGR P06401 1/20 0.35
▸ MAPK9 P45984 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16622784 0.98 L3MBTL1 (0.58) KDM4EL3MBTL1ATMIL1R1KMT2A
SCHEMBL18388795 0.93 KDM4E (0.50) KDM4EL3MBTL1ATMIL1R1KMT2A
SCHEMBL5999723 0.91 L3MBTL1 (0.72) KDM4EL3MBTL1ATMIL1R1KMT2A
SCHEMBL29354385 0.91 L3MBTL1 (0.72) KDM4EL3MBTL1ATMIL1R1KMT2A
SCHEMBL29387946 0.91 L3MBTL1 (0.72) KDM4EL3MBTL1ATMIL1R1KMT2A
SCHEMBL14900748 0.91 L3MBTL1 (0.72) KDM4EL3MBTL1ATMIL1R1KMT2A
SCHEMBL11981068 0.91 L3MBTL1 (0.72) KDM4EL3MBTL1ATMIL1R1KMT2A
SCHEMBL29431010 0.91 L3MBTL1 (0.72) KDM4EL3MBTL1ATMIL1R1KMT2A
SCHEMBL11981026 0.91 L3MBTL1 (0.72) KDM4EL3MBTL1ATMIL1R1KMT2A
SCHEMBL18381789 0.90 L3MBTL1 (0.69) KDM4EL3MBTL1ATMIL1R1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11691991-B2 Compound, a display panel and a display device Shanghai Tianma AM-OLED Co., Ltd. (CN) 2023-07-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11691991-B2 Compound, a display panel and a display device BROX, BRSK1, BRSK2 KDM4E 3870/4885L3MBTL1 3452/4885ATM 4117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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