SCHEMBL18390208

SCHEMBL18390208

B[C@@H]1O[C@H](CO)C(O[PH](=O)O)C1OCCOC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16729887 1.00 LGALS8 (0.30) LGALS8
SCHEMBL14478380 0.89 — —
SCHEMBL19631498 0.85 LGALS8 (0.33) LGALS8
SCHEMBL12292292 0.84 LGALS8 (0.33) LGALS8
SCHEMBL20334521 0.84 LGALS8 (0.33) LGALS8
SCHEMBL13447823 0.84 LGALS8 (0.35) LGALS8
SCHEMBL19661469 0.84 LGALS8 (0.33) LGALS8
SCHEMBL23417369 0.83 MAPK1 (0.42) LGALS8
SCHEMBL22605123 0.83 MAPK1 (0.42) LGALS8
SCHEMBL22605122 0.83 MAPK1 (0.42) LGALS8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11001835-B2 Method for the synthesis of a bifunctional complex NUEVOLUTION A/S (DK) 2021-05-11 — — US disclosed
US-9725723-B2 Compositions and methods for modulation of FGFR3 expression ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) 2017-08-08 — — US disclosed
EP-2336315-B1 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION AS (DK) 2017-07-19 — — EP disclosed
US-20170015697-A1 SPLICE SWITCHING OLIGOMERS FOR TNF SUPERFAMILY RECEPTORS AND THEIR USE IN TREATMENT OF DISEASE SANTARIS PHARMA A/S (DK) 2017-01-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170015697-A1 SPLICE SWITCHING OLIGOMERS FOR TNF SUPERFAMILY RECEPTORS AND THEIR USE IN TREATMENT OF DISEASE TNFRSF1A, TNFRSF9, CD40 LGALS8 3033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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